1,290 results found
    1. Epidemiology and Global Health

    Development of a confinable gene drive system in the human disease vector Aedes aegypti

    Ming Li et al.
    Highly efficient and confinable split gene drives are a new tool for the control of the dengue mosquito vector.
    1. Genetics and Genomics

    Molecular safeguarding of CRISPR gene drive experiments

    Jackson Champer et al.
    Genes drives utilizing synthetic target sites and the split-Cas9 system have similar performance to standard drives.
    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic et al.
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Point of View: Looking back and looking forward at Janelia

    Gerald M Rubin, Erin K O'Shea
    The Janelia Research Campus opened its doors 12 years ago: we describe the philosophy underpinning Janelia, the lessons learned, and plans for the future.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Phenotypic Diversity: Setting the bar

    Charles Y Feigin, Ricardo Mallarino
    Analyzing the genomes of rock pigeons demonstrates that genetic variation comes in many forms and can have unexpected origins.
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    1. Cell Biology
    2. Neuroscience

    2018 Gairdner Awards: The past, present and future of light-gated ion channels and optogenetics

    Sheena A Josselyn
    Research into light-gated ion channels called channelrhodospins laid the foundations for the development of optogenetics, a technique that has gone on to revolutionize neuroscience.
    1. Ecology
    2. Evolutionary Biology

    The Natural History of Model Organisms: Advancing biology through a deeper understanding of zebrafish ecology and evolution

    David M Parichy
    The zebrafish is a premier model organism for biomedical research, with a rich array of tools and genomic resources, and combining these with a fuller appreciation of wild zebrafish ecology could greatly extend its utility in biological research.
    1. Neuroscience

    Science Forum: Ten common statistical mistakes to watch out for when writing or reviewing a manuscript

    Tamar R Makin, Jean-Jacques Orban de Xivry
    What can authors and reviewers do to keep common statistical mistakes out of the literature?
    1. Evolutionary Biology

    The Natural History of Model Organisms: Insights into the evolution of social systems and species from baboon studies

    Julia Fischer et al.
    Wild baboons are an excellent model to study complex evolutionary processes such as speciation and hybridization, as well as the links between sociality, longevity and reproductive success.
    1. Ecology
    2. Human Biology and Medicine

    Point of View: A transatlantic perspective on 20 emerging issues in biological engineering

    Bonnie C Wintle et al.
    Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.

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