Browse the search results

Page 2 of 224
    1. Physics of Living Systems

    Spontaneous body wall contractions stabilize the fluid microenvironment that shapes host–microbe associations

    Janna C Nawroth, Christoph Giez ... Thomas CG Bosch
    Spontaneous contractions allow shedding of the fluid boundary layer and thereby stabilize microbiota.
    1. Neuroscience

    Impaired astrocytic Ca2+ signaling in awake-behaving Alzheimer’s disease transgenic mice

    Knut Sindre Åbjørsbråten, Gry HE Syverstad Skaaraas ... Rune Enger
    Noradrenaline-mediated astrocytic Ca2+ signaling in behavior is reduced in awake-behaving tg-ArcSwe Alzheimer's disease transgenic mice.
    1. Neuroscience

    Behavioral control by depolarized and hyperpolarized states of an integrating neuron

    Aylesse Sordillo, Cornelia I Bargmann
    Precise genetic manipulations demonstrate that a single-neuron class dynamically controls multiple behaviors by engaging different synapses during high- and low-activity states.
    1. Neuroscience

    Target-specific membrane potential dynamics of neocortical projection neurons during goal-directed behavior

    Takayuki Yamashita, Carl CH Petersen
    A learning-induced, motor-related, projection-specific signal from S1 to S2 accompanies reward-based-learning of a goal-directed sensorimotor transformation of whisker sensation into licking motor output.
    1. Neuroscience

    Acquisition of innate odor preference depends on spontaneous and experiential activities during critical period

    Qiang Qiu, Yunming Wu ... C Ron Yu
    A delicate balance of neural activity is required during critical period in establishing innate odor preference.
    1. Neuroscience

    Neural signatures of auditory hypersensitivity following acoustic trauma

    Matthew McGill, Ariel E Hight ... Daniel B Polley
    Chronic two-photon calcium imaging, optogenetics, and operant behavioral approaches were leveraged to show that hyperactivity, hyperresponsivity, and hypersynchronization in auditory cortex neural ensembles can account for auditory hypersensitivity following acoustic trauma.
    1. Neuroscience

    Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1

    J Elliott Robinson, Gerard M Coughlin ... Viviana Gradinaru
    Heterozygous Nf1 knockout mice exhibit distinct dopaminergic phenotypes in vivo, as revealed by the genetically encoded dopamine sensor dLight1, patch clamp electrophysiology, optogenetics, and novel viral tools for morphological analysis.
    1. Neuroscience

    The manifold structure of limb coordination in walking Drosophila

    Brian D DeAngelis, Jacob A Zavatone-Veth, Damon A Clark
    During walking and turning, the fruit fly Drosophila uses variable limb coordination patterns, which exist on a low-dimensional, continuous manifold.
    1. Neuroscience

    Causal roles of prefrontal cortex during spontaneous perceptual switching are determined by brain state dynamics

    Takamitsu Watanabe
    Prefrontal causal roles in bistable perception are dynamically changing and determined by the brain state to which the whole-brain activity pattern belongs.
    1. Ecology
    2. Evolutionary Biology

    The evolution of distributed sensing and collective computation in animal populations

    Andrew M Hein, Sara Brin Rosenthal ... Iain D Couzin
    A computational model shows that natural selection can cause populations to evolve a distinctive population-level phenotype: the ability to transition between collective states in response to the environment.