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    1. Evolutionary Biology

    Digital restoration of the pectoral girdles of two Early Cretaceous birds and implications for early-flight evolution

    Shiying Wang, Yubo Ma ... Xing Xu
    New digital restorations indicate that the structure and function of the shoulder joint were highly variable among Early Cretaceous birds, with such key features as the configuration of the triosseal canal and the nature of scapula-coracoid articulation showing considerable diversity.
    1. Computational and Systems Biology
    2. Neuroscience

    Olfactory responses of Drosophila are encoded in the organization of projection neurons

    Kiri Choi, Won Kyu Kim, Changbong Hyeon
    The organization of olfactory projection neurons and their synaptic connectivity with third-order neurons studied along with olfactory responses suggest that the labeled-line design is partially at work in the Drosophila olfactory system.
    1. Neuroscience

    Prediction error and repetition suppression have distinct effects on neural representations of visual information

    Matthew F Tang, Cooper A Smout ... Jason B Mattingley
    Multivariate analyses of human electrophysiological recordings revealed that the brain represents unexpected visual stimuli with greater fidelity than expected stimuli which arose independently of simple habituation arising from repetition.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Dynamics of ribosomes and release factors during translation termination in E. coli

    Sarah Adio, Heena Sharma ... Marina V Rodnina
    Translation termination is a stochastic process that utilizes loosely coupled motions of its players to complete protein synthesis and release the newly synthesized nascent chain toward its cellular destination.
    1. Genetics and Genomics

    CLAMP and Zelda function together to promote Drosophila zygotic genome activation

    Jingyue Duan, Leila Rieder ... Erica Larschan
    Maternal CLAMP functions as a novel pioneer transcription factor to open chromatin and plays a targeted yet essential role in Drosophila zygotic genome activation.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice

    Clare M Smith, Richard E Baker ... Christopher M Sassetti
    A novel dual genome approach that combines genetically diverse mice and a library of bacterial mutants to define the genome-wide host pathogen interactions that drive distinct outcomes to tuberculosis.
    1. Neuroscience

    Homeostatic plasticity fails at the intersection of autism-gene mutations and a novel class of common genetic modifiers

    Özgür Genç, Joon-Yong An ... Graeme W Davis
    Forward genetic screens define a novel genetic landscape by which diverse, unrelated autism risk genes may converge to commonly affect the robustness of synaptic transmission.
    1. Physics of Living Systems
    2. Developmental Biology

    Unified quantitative characterization of epithelial tissue development

    Boris Guirao, Stéphane U Rigaud ... Yohanns Bellaïche
    A new approach measures the respective participations of elementary cell behaviors – such as cell division, intercalation, shape change and death – in the shaping of animal tissues.
    1. Neuroscience

    A Statistical Framework for Analysis of Trial-Level Temporal Dynamics in Fiber Photometry Experiments

    Gabriel Loewinger, Erjia Cui ... Francisco Pereira
    Revised
    Reviewed Preprint v2
    Updated
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    1. Evolutionary Biology
    2. Genetics and Genomics

    Polygenic adaptation from standing genetic variation allows rapid ecotype formation

    Nico Fuhrmann, Celine Prakash, Tobias S Kaiser
    Baltic and Arctic ecotypes of the marine midge Clunio emerged from a recent adaptive radiation, which is based on standing genetic variation at many loci involved in time-keeping and nervous system development.