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    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II

    Raphael Vidal, Eoin Leen ... Gabriele Büchel
    MYCN and TFIIIC exert a censoring function during early transcription, limiting the accumulation of inactive RNAPII at the promoter and facilitating promoter-proximal degradation of nascent RNA.
    1. Ecology

    Near infrared radiation-driven oxygenic photosynthesis contributes substantially to primary production in biofilms harboring chlorophyll f-containing cyanobacteria

    Maria Mosshammer, Erik CL Trampe ... Michael Kühl
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Computational and Systems Biology

    Convergent evolution in silico reveals shape and dynamic principles of directed locomotion

    Renata B Biazzi, André Fujita, Daniel Y Takahashi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Microbiology and Infectious Disease

    Glycan-shielded homodimer structure and dynamical features of the canine distemper virus hemagglutinin relevant for viral entry and efficient vaccination

    Hideo Fukuhara, Kohei Yumoto ... Katsumi Maenaka
    X-ray crystallographic and atomic force microscopic analyses reveal the tilted homodimer structure and unanticipated dynamic characteristics of canine distemper virus-hemagglutinin (CDV-H), providing insights into the molecular and dynamic processes of Morbillivirus for cell entry, effective immunizations, and vaccine/drug design.
    1. Neuroscience

    Whole-body connectome of a segmented annelid larva

    Csaba Verasztó, Sanja Jasek ... Gáspár Jékely
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Physics of Living Systems

    Quantifying gliding forces of filamentous cyanobacteria by self-buckling

    Maximilian Kurjahn, Antaran Deka ... Stefan Karpitschka
    The self-buckling behavior of filamentous cyanobacteria allowed a quantification of their propulsion forces, indicating that adhesion plays an important role in gliding motility.
    1. Neuroscience

    Pan-cortical 2-photon mesoscopic imaging and neurobehavioral alignment in awake, behaving mice

    Evan D Vickers, David A McCormick
    Procedures were developed to perform mesoscale 2-photon Ca2+ imaging simultaneously from all of mouse dorsolateral neocortex, facilitating identification of widespread neural ensembles with activity related to diverse aspects of behavior.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Remodeling of skeletal muscle myosin metabolic states in hibernating mammals

    Christopher TA Lewis, Elise G Melhedegaard ... Julien Ochala
    During hibernation, animals remodel the structure of their relaxed muscle via a protein called myosin and this enables vast temperature changes.
    1. Ecology
    2. Evolutionary Biology

    Evolutionary trade-offs in dormancy phenology

    Théo Constant, F Stephen Dobson ... Sylvain Giroud
    Dormancy during non-life-threatening periods that are unfavorable for reproduction may be more widespread than previously appreciated.
    1. Physics of Living Systems

    Theory of active self-organization of dense nematic structures in the actin cytoskeleton

    Waleed Mirza, Marco De Corato ... Marino Arroyo
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete