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    1. Developmental Biology
    2. Physics of Living Systems

    The geometric basis of epithelial convergent extension

    Fridtjof Brauns, Nikolas H Claussen ... Boris I Shraiman
    Active and passive contributions to cell shape change and rearrangements can be distinguished from observed cell geometry, revealing the self-organization mechanisms underlying internally-driven epithelial convergent extension.
    1. Cell Biology

    Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance

    Atsushi Matsumoto, Akihito Inoko ... Junichi Ikenouchi
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cancer Biology

    Increased inflammatory signature in myeloid cells of non-small cell lung cancer patients with high clonal hematopoiesis burden

    Hyungtai Sim, Hyun Jung Park ... Murim Choi
    In metastatic NSCLC patients, CHIP showed minimal impact on immunotherapy response but was more prevalent and associated with inflammatory pathways in myeloid cells, particularly in lung squamous cell carcinoma.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition

    Gülnihal Kavaklıoğlu, Alexandra Podhornik ... Christian Seiser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Microbiology and Infectious Disease
    2. Cancer Biology

    The long noncoding RNA lnc-FANCI-2 intrinsically restricts RAS signaling and phosphorylation of Akt and Erk in HPV16-infected cervical cancer

    Haibin Liu, Lulu Yu ... Zhi-Ming Zheng
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cancer Biology

    Low-dose chemotherapy combined with delayed immunotherapy in the neoadjuvant treatment of non-small cell lung cancer and dynamic monitoring of the drug response in peripheral blood

    Chaoyang Liang, Qi Song ... Bo Yang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Stem Cells and Regenerative Medicine

    The Jag2/Notch1 signaling axis promotes sebaceous gland differentiation and controls progenitor proliferation

    Syeda Nayab Fatima Abidi, Sara Chan ... Christian W Siebel
    Inhibition of Notch signaling through the Jag2 ligand, blocks homeostatic sebocyte differentiation, and pushes the cells to a progenitor fate, in a reversible manner.
    1. Cancer Biology

    STAMBPL1 activates the GRHL3/HIF1A/VEGFA axis through interaction with FOXO1 to promote angiogenesis in triple-negative breast cancer

    Huan Fang, Huichun Liang ... Ceshi Chen
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cancer Biology

    PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP

    Jiongke Wang, Yujie Shi ... Qianming Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Incomplete
    1. Genetics and Genomics
    2. Cancer Biology

    Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer

    Arkajyoti Bhattacharya, Thijs S Stutvoet ... Rudolf SN Fehrmann
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
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