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An unprecedented large-scale screen in mice for morphogenetic regulators of tissue development provides major new insights into the roles of Rho GTPases in diverse array of skin developmental processes.

The modulatory neurochemicals acetylcholine and dopamine are released differentially into the basolateral amygdala depending on the emotional content of vocalizations and the sex, hormonal state, and experience of listening animals.

Functionalized protein binders, anchored to specific regions along the cell cortex, provide a novel approach to directly modify protein localization and dispersal in vivo.

The molecular mechanism that candidalysin uses to perforate membranes is unraveled, which opens the door to the rational design of inhibitors against candidiasis.

PRMT5 participates in ovarian granulosa cell lineage maintenance by regulating Wt1 IRES-dependent translation.

Computational, theoretical, and in vivo studies reveal that in epithelia the self-organization of apical microtubules is robustly determined by cell geometry and minus-end distribution, not organism environment or genetics.

X-ray histotomography produces the first 3-dimensional images with the combined submicron resolution, centimeter fields-of-view, soft-tissue contrast, and potential throughput to enable quantitative, histopathological and centimeter-scale phenotyping for whole-organism phenomics.

Engagement of both host and parasite signaling pathways proves a novel approach for developing improved anti-parasitic therapies.

Genetic analyses reveal the importance of dynamic protein processing at the apical cell membrane in response to forces damaging cell membranes during tube expansion in tubular organs.

Single nucleus and single cell RNA-seq data uncover novel transcriptomic perspectives in Drosophila testis biology and provide access to user-friendly tools for further scientific discovery in the field.