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    1. Neuroscience

    Detecting changes in dynamic and complex acoustic environments

    Yves Boubenec et al.
    Psychophysics experiments and EEG recordings reveal that people's performance in detecting unexpected changes in complex auditory scenes can be modeled as a process of sensory evidence accumulation.
    1. Computational and Systems Biology

    Calibration and analysis of genome-based models for microbial ecology

    Stilianos Louca, Michael Doebeli
    A novel computation tool for microbial community modeling predicts the evolution and diversification of E. coli in laboratory evolution experiments and gives insight into the underlying metabolic processes.
    1. Epidemiology and Global Health
    2. Medicine

    Mapping the endemicity and seasonality of clinical malaria for intervention targeting in Haiti using routine case data

    Ewan Cameron et al.
    A demonstration of the power of routine case data and statistical modelling to guide the allocation of anti-malarial interventions in a resource-constrained setting.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Listeria monocytogenes cell-to-cell spread in epithelia is heterogeneous and dominated by rare pioneer bacteria

    Fabian E Ortega et al.
    The pathogenic bacterium Listeria monocytogenes spreads infection using a two-tiered strategy, where most bacteria spread locally but a few 'pioneers' move further, increasing the likelihood of a persistent infection.
    1. Neuroscience

    Neuronal variability and tuning are balanced to optimize naturalistic self-motion coding in primate vestibular pathways

    Diana E Mitchell et al.
    A match between neuronal variability and tuning enables optimized coding of natural self-motion in early vestibular pathways.
    1. Epidemiology and Global Health

    Evaluating distributional regression strategies for modelling self-reported sexual age-mixing

    Timothy M Wolock et al.
    Integrating the sinh-arcsinh distribution into a distributional regression framework allows us to produce precise, local estimates of sexual age-mixing, facilitating more accurate modelling of sexually transmitted disease dynamics.
    1. Neuroscience

    Impaired adaptation of learning to contingency volatility in internalizing psychopathology

    Christopher Gagne et al.
    Hierarchical modeling of internalizing symptoms and task performance reveals that difficulty adapting probabilistic learning to second-order uncertainty is common to anxiety and depression and holds across rewarding and punishing outcomes.
    1. Neuroscience

    An afferent white matter pathway from the pulvinar to the amygdala facilitates fear recognition

    Jessica McFadyen et al.
    A subcortical white matter connection from the pulvinar to the amygdala predicts how well we recognise fearful faces and the strength of feed-forward neural connectivity.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    The intractable challenge of evaluating cattle vaccination as a control for bovine Tuberculosis

    Andrew James Kerr Conlan et al.
    Natural transmission experiments should be prioritised over risky and expensive field trials, in order to establish the impact of cattle vaccination on the transmission of bovine Tuberculosis.
    1. Epidemiology and Global Health
    2. Medicine

    Conjunction of factors triggering waves of seasonal influenza

    Ishanu Chattopadhyay et al.
    Three complementary computational approaches reveal a set of putative causes of initiation of pan-USA waves of influenza.