445 results found
    1. Microbiology and Infectious Disease

    Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway

    Xin Ma, Meng Li ... Xinyan Han
    FMT alleviated the intestinal barrier damage caused by enterotoxigenic Escherichia coli infection in antibiotic-induced microbiome-disordered model through increasing the relative abundance of A. muciniphila in the intestine.
    1. Developmental Biology
    2. Cancer Biology

    Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

    Denise Ragusa, Chun-Wai Suen ... Cristina Pina
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Inadequate
    1. Developmental Biology
    2. Neuroscience

    Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo

    Taro Ichimura, Taishi Kakizuka ... Takeharu Nagai
    Volumetric trans-scale imaging with a subcellular resolution across a wide field-of-view of 1.5 × 1.0 cm2 has been realized, facilitating the analysis of cellular dynamics during embryogenesis and brain function.
    1. Cell Biology

    ScRNA-seq and scATAC-seq reveal that sertoli cell mediate spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia

    Shimin Wang, Hongxian Wang ... Dong Zhao
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    • Incomplete
    1. Stem Cells and Regenerative Medicine

    Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

    Sujeethkumar Prithiviraj, Alejandro Garcia Garcia ... Paul E Bourgine
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Stem Cells and Regenerative Medicine

    Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial

    Shiyu Zhang, Min Zhou ... Wei Zuo
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation

    Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism

    Mengyun Li, Huan Jin ... Xiaojun Xia
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro

    Paolo Petazzi, Telma Ventura ... Antonella Fidanza
    A novel tool is used to assess gene function in vitro by targeted endogenous transcriptional activation to unveil novel players in development and disease.

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