22 results found
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    A recurrent regulatory change underlying altered expression and Wnt response of the stickleback armor plates gene EDA

    Natasha M O'Brown et al.
    An identical DNA base pair change has occurred in divergent sticklebacks to alter the expression of a major developmental gene controlling armor plates, thus providing a molecular link between particular enhancer changes, cell signaling, and repeated skeletal evolution in natural populations.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Predominance of cis-regulatory changes in parallel expression divergence of sticklebacks

    Jukka-Pekka Verta, Felicity C Jones
    Cis-regulation such as enhancers and promoters plays a major role in parallel gene expression divergence and has features that make it a well-poised substrate for adaptive evolution.
    1. Developmental Biology

    Ancient origin of lubricated joints in bony vertebrates

    Amjad Askary et al.
    Zebrafish have lubricated joints similar to ours and are a tractable model for arthritis research.
    1. Developmental Biology
    2. Evolutionary Biology

    A novel enhancer near the Pitx1 gene influences development and evolution of pelvic appendages in vertebrates

    Abbey C Thompson et al.
    Regulatory sequences downstream of a key limb identity gene are required for normal sizes of leg bones, and are changed in wild species with dramatic alterations in pelvic structures.
    1. Genetics and Genomics

    The genetic basis for ecological adaptation of the Atlantic herring revealed by genome sequencing

    Alvaro Martinez Barrio et al.
    Whole genome sequencing of 19 populations of Atlantic and Baltic herring reveals hundreds of individual loci underlying adaptation to a low salinity niche or timing of reproduction.
    1. Genetics and Genomics

    High-resolution mapping reveals hundreds of genetic incompatibilities in hybridizing fish species

    Molly Schumer et al.
    Genetic incompatibilities are common and widely distributed throughout the genomes of swordtail fish, and prevent the regions of the genome around them from being exchanged between different species.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Non-classical amine recognition evolved in a large clade of olfactory receptors

    Qian Li et al.
    Fish trace amine-associated receptors evolved a novel structural motif that enables the detection of chemically diverse amine odors in a non-canonical 'inverted' orientation.
    1. Developmental Biology
    2. Evolutionary Biology

    An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice

    João PL Castro et al.
    Genome sequencing of mice selected for longer limbs reveals that rapid selection response is due to both discrete loci and polygenic adaptation.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity

    Pierre Khoueiry et al.
    Interspecies comparison of transcription factor occupancy during embryogenesis reveals potential co-operative relationships between factors and uncovers the inherent plasticity of developmental enhancers to overcome divergence in transcription factor occupancy.
    1. Genetics and Genomics

    Genome-wide mapping in a house mouse hybrid zone reveals hybrid sterility loci and Dobzhansky-Muller interactions

    Leslie M Turner, Bettina Harr
    The genomic regions that cause male hybrids between house mouse subspecies to have low fertility have been identified.

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