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    1. Developmental Biology
    2. Evolutionary Biology

    Early maternal loss leads to short- but not long-term effects on diurnal cortisol slopes in wild chimpanzees

    Cédric Girard-Buttoz, Patrick J Tkaczynski ... Catherine Crockford
    Wild chimpanzees contrast to humans since adult male chimpanzees do not exhibit physiological indicators of biological embedding of the stress associated to maternal loss early in life.
    1. Neuroscience

    Interplay between external inputs and recurrent dynamics during movement preparation and execution in a network model of motor cortex

    Ludovica Bachschmid-Romano, Nicholas G Hatsopoulos, Nicolas Brunel
    A recurrent neural network model with parameters constrained by data explains mechanisms for how tuning properties of motor cortical neurons change during movement preparation and execution in a monkey performing a reaching task, and accurately reproduces neural dynamics from recordings.
    1. Genetics and Genomics
    2. Neuroscience

    A genetic, genomic, and computational resource for exploring neural circuit function

    Fred P Davis, Aljoscha Nern ... Gilbert L Henry
    Transcriptomes of cells in the Drosophila visual system combined with anatomy and other information reveal new functional insight into the visual circuit.
    1. Neuroscience

    Population response magnitude variation in inferotemporal cortex predicts image memorability

    Andrew Jaegle, Vahid Mehrpour ... Nicole Rust
    Population response magnitude predicts how well an image will be remembered, in both monkey inferotemporal cortex and neural networks trained to categorize objects.
    1. Computational and Systems Biology

    Efficient coding in biophysically realistic excitatory-inhibitory spiking networks

    Veronika Koren, Simone Blanco Malerba ... Stefano Panzeri
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos

    Marius Regin, Yingnan Lei ... Claudia Spits
    Aneuploid human embryonic cells are eliminated by p53-mediated apoptosis in a gene dosage dependent manner.
    1. Neuroscience

    Olfactory ensheathing cells from adult female rats are hybrid glia that promote neural repair

    Patricia E Phelps, Sung Min Ha ... Xia Yang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution

    Michael Luke Carlson, John William Young ... Franck Duong
    A simple, yet elegant method for robust self-assembly of diverse membrane proteins into soluble peptide nanoparticles for their structural and functional analysis in detergent-free solutions.
    1. Physics of Living Systems
    2. Cell Biology

    Mechanical heterogeneity along single cell-cell junctions is driven by lateral clustering of cadherins during vertebrate axis elongation

    Robert J Huebner, Abdul Naseer Malmi-Kakkada ... John B Wallingford
    Very local molecular patterns impart precise changes in the local mechanics of individual cell-cell junctions.
    1. Neuroscience

    A unifying account of replay as context-driven memory reactivation

    Zhenglong Zhou, Michael J Kahana, Anna C Schapiro
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling