115 results found
    1. Medicine

    A new preprocedural predictive risk model for post-endoscopic retrograde cholangiopancreatography pancreatitis: The SuPER model

    Mitsuru Sugimoto, Tadayuki Takagi ... Hiromasa Ohira
    A PEP risk scoring model that could be calculated before ERCP, SuPER model, may aid in preventing PEP by allowing selection of the appropriate expert endoscopist and useful PEP prophylaxes.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    N-terminus of Drosophila melanogaster MSL1 is critical for dosage compensation

    Valentin Babosha, Natalia Klimenko ... Oksana Maksimenko
    N‑terminus of MSL1 protein, involved in dosage compensation in Drosophila, is required for the interaction with non-coding roX2 RNA and the assembly of the complex on the male X chromosome.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Endogenous oligomer formation underlies DVL2 condensates and promotes Wnt/β-catenin signaling

    Senem Ntourmas, Martin Sachs ... Dominic B Bernkopf
    Biochemical detection of endogenous, paralog-specific DVL2 complexes, molecular characterization of underlying protein domains and functional evidence for their importance extend the knowledge of Wnt pathway regulation through DVL2 biomolecular condensates.
    1. Stem Cells and Regenerative Medicine

    Dynamic tracking of native precursors in adult mice

    Suying Liu, Sarah E Adams ... Peter Kurre
    A revised analytical framework grounded in the principle of binomial distribution captures the full clonality and dynamic shifts of hematopoiesis throughout ontogeny.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons

    Ana C Costa, Blanca R Murillo ... Monica M Sousa
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Dynamics of antimicrobial resistance and virulence of Salmonella enterica serovar Dublin

    Cheryll M Sia, Rebecca L Ambrose ... Danielle J Ingle
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Neuroscience

    Multi-level processing of emotions in life motion signals revealed through pupil responses

    Tian Yuan, Li Wang, Yi Jiang
    Intact and local emotional biological motion exerted distinct influences on pupil responses, wherein the emotional modulation observed in intact biological motion is linked to individual autistic traits.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Insulator-based dielectrophoresis-assisted separation of insulin secretory vesicles

    Mahta Barekatain, Yameng Liu ... Mark A Hayes
    An unbiased separation method reveals distinct subpopulations of insulin secretory vesicles that undergo dynamic remodeling upon glucose stimulation.
    1. Biochemistry and Chemical Biology

    Probing PAC1 receptor activation across species with an engineered sensor

    Reto B Cola, Salome N Niethammer ... Tommaso Patriarchi
    A new genetically encoded sensor robustly detects exogenously applied PAC1R ligands in vitro, ex vivo, and in vivo (in zebrafishes and mice) serving as a useful resource for probing PAC1R functions.
    1. Ecology

    Adipokinetic hormone signaling mediates the enhanced fecundity of Diaphorina citri infected by ‘Candidatus Liberibacter asiaticus’

    Jiayun Li, Paul Holford ... Xiaoge Nian
    Molecular mechanism that Candidatus Liberibacter asiaticus improves the lipid metabolism and fecundity of Diaphorina citri through adipokinetic hormone and its receptor.

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