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    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Bone-Targeting Drugs: From vesicle to cytosol

    Michael J Rogers, Marcia A Munoz
    Drugs called bisphosphonates are used to treat a range of bone diseases, but how do they reach the enzymes that are their target?
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    1. Microbiology and Infectious Disease

    Research: A comprehensive and quantitative exploration of thousands of viral genomes

    Gita Mahmoudabadi, Rob Phillips
    A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.
    1. Cell Biology

    mRNA Decay: How cells kill a "killer" messenger

    Cosmin Saveanu, Alain Jacquier
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    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Oncogenesis: Taking the brakes off telomerase

    Kamila Naxerova, Stephen J Elledge
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    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Translational Control: An emergency brake for protein synthesis

    Vladislava Hronová, Leoš Shivaya Valášek
    The integrated stress response is able to rapidly shut down the synthesis of proteins in eukaryotic cells.
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  1. Research: Decoupling of the minority PhD talent pool and assistant professor hiring in medical school basic science departments in the US

    Kenneth D Gibbs Jr et al.
    A systems-level analysis of the biomedical workforce in the US shows that current strategies to enhance faculty diversity are unlikely to have a significant impact, and that there is a need to increase the number of PhDs from underrepresented minority backgrounds who move on to postdoctoral positions.
    1. Ecology

    Point of View: A transatlantic perspective on 20 emerging issues in biological engineering

    Bonnie C Wintle et al.
    Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.
    1. Cell Biology
    2. Computational and Systems Biology

    Science Forum: The Human Cell Atlas

    Aviv Regev et al.
    Advances in techniques for analysing single cells and tissues have inspired an international effort to create comprehensive reference maps of all human cells - the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring and treating disease.
    1. Cell Biology

    Toll-like Receptors: Different routes to the same destination

    Kachiko Hayashi, Akiko Iwasaki
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