Katherine A Senn, Karli A Lipinski ... Aaron A Hoskins
The Saccharomyces cerevisiae spliceosome component Fyv6 contributes to precursor messenger RNA splicing by promoting use of branch site distal 3' splice sites and interacting with key factors involved in exon ligation.
Sebastian Hillringhaus, Anil K Dasanna ... Dmitry A Fedosov
The bond-based adhesion model is a key step toward a realistic description of RBC-parasite interaction, which allows the investigation of more realistic scenarios and is relevant for other biological systems.
Intracellular growth of the bacterial pathogen Legionella pneumophila in the amoeba Dictyostelium discoideum implicates a bacterial fatty acid transporter as well as dynamic interactions of the distinct membrane-bound replication compartment with host cell lipid droplets.
Epithelial to mesenchymal transition (EMT) is a continuous process, in which the transition or intermediate states can be molecularly and spatially defined, shedding new light on development and disease EMT.
Johanna Lattner, Weihua Leng ... David Flores-Benitez
The polarity protein crumbs controls apical secretion and the architecture of the apical domain by modulating PI(4,5)P2 levels and the organization of apical Rab6-, Rab11-, and Rab30-dependent trafficking.
Mathias L Heltberg, Judith Miné-Hattab ... Thierry Mora
Two competing descriptions of membrane-less sub-compartments, liquid droplets and polymer binding aggregates, can be cast into a common theoretical framework and tested through single-particle tracking experiments.
By using a specialized camera that corrects for eye blur, millions of single-blood-cells are imaged, and their speed measured, as they travel through the largest-to-smallest vessels of the retina.