5,015 results found
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    Energetics and conformational pathways of functional rotation in the multidrug transporter AcrB

    Yasuhiro Matsunaga et al.
    High-performance computing simulations reveal how two remote sites in the multidrug transporter AcrB work together for drug extrusion using the proton-motive force.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    CATaDa reveals global remodelling of chromatin accessibility during stem cell differentiation in vivo

    Gabriel N Aughey et al.
    A new method for in vivo cell-specific profiling of chromatin accessibility reveals local and global chromatin dynamics during the differentiation of neural and gut stem cell lineages.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity

    Pascal Krotee et al.
    Atomic structures of hIAPP fibrillar segments, determined using the cryo electron microscopy method MicroED, reveal that strong, stable intermolecular interactions are important features of cytotoxic amyloid proteins.

Refine your results by:

Type
Research categories