Targeted therapies induce an aberrant fucosylation of complex tumor secretomes stimulating the expansion of minority drug-resistant clones and promoting therapy resistance.
The number of inflows and outflows at the occluded capillary governs the local flow reduction, and the different topological configurations are probably designed for distinct functional tasks.
The comprehension of acoustic and visual speech depends on modality-specific pathways in the brain, which explains why auditory speech abilities and lip reading are not associated in typical adults.
Early and late visual deprivation trigger a redeployment mechanism that reallocate part of the processing typically tagging the preserved senses (i.e. the temporal cortex for auditory stimulation) to the occipital cortex deprived of its most salient visual input.
Placing the PACAP/PAC1 signaling within glutamate/GABA cell type and subregional contexts in mouse brain reveals its conspicuous role for sensorimotor circuit interaction through modulating neuronal plasticity.
The human body shapes how we perceive and interact with the environment, with body size serving as a boundary for defining potential actions, hereby enlightening research on foundation agents.
R A Greenstein, Stephen K Jones ... Bassem Al-Sady
Heterochromatin spreading in fission yeast predominantly produces intergenerationally unstable outcomes, requiring an accessory element that represses histone turnover.