Judith Hüttemeister, Franziska Rudolph ... Michael Gotthardt
Titin’s regulated integration and mobility after cell fusion support syncytium formation in culture, while limited diffusion in vivo highlights a key challenge for developing effective cell-based therapies for skeletal muscle diseases.
Anne Drougard, Eric H Ma ... John Andrew Pospisilik
High-fat ingestion triggers microglial metabolic activation within a single feeding cycle, and enhances whole-body metabolism and memory by converting fatty acids into protective substrates for surrounding neurons.
Two alternative models of PKA activation were tested in neurons, and the results support the classical model in which the catalytic subunit dissociated from the regulatory subunit upon activation.
Coupling between subcellular localization and protein turnover of a neuronal stress kinase, DLK, and its role in neuronal stress responses in Drosophila.
A single-cell RNA sequencing reveals cell heterogeneity of secondary metabolism in tea plant root and a proposed model in which the theanine biosynthesis pathway occurs via multicellular compartmentation.
