An analysis of the first complete synaptic resolution connectome of Drosophila's navigation circuit uncovers neural network motifs supporting broadly relevant sensorimotor computations.

Specific memories can be stored through changes in the postsynaptic cholinergic receptor composition at Drosophila mushroom body synapses.

Bacillus thuringiensis crystalline toxins used as microbial pesticides disrupt the homeostasis of intestinal cells of the non-target Drosophila melanogaster.

Distinct and direct functions of the RNA binding protein SAM68 regulate integrin signaling and focal adhesion dynamics that condition basement membrane deposition and angiogenic behavior of endothelial cells.

Chronic inhibition of mTORC1 signaling strongly affects the morphology, physiology and output of dopamine neurons leading to impaired dopaminergic function in mice.

High-fat ingestion triggers microglial metabolic activation within a single feeding cycle, and enhances whole-body metabolism and memory by converting fatty acids into protective substrates for surrounding neurons.

Purkinje cells of the cerebellum, a conserved vertebrate brain region important for sensorimotor integration, receive sensory and motor information from distinct input streams and are functionally clustered into modules reflecting the larval zebrafish's behavioral repertoire.

Discovery of a novel long non-coding RNA overlapping the distal SOX17 enhancer (eSOX17) that plays an essential role in human endoderm development.