Two distinct projections from the basolateral amygdala to nucleus accumbens differentially contribute to cue- versus reward-mediated behavioral reinforcement.
There is substantial individual variation in behavioral and neural responses to acute ketamine administration in healthy controls, which emphasises the need for personalized approaches when harnessing ketamine as a treatment for depression.
Abigail M Polter, Kelsey Barcomb ... Julie A Kauer
Rats exposed to a single stressful event experience days-long constitutive activation of the kappa opioid receptor at inhibitory synapses in part of the brain’s reward system, which increases their drug-seeking behavior.
Allison Schad, Rebekah L Layton ... Jeanette Gowen Cook
Biomedical doctoral students and those from historically excluded groups exhibit higher rates of mental distress, which worsened in 2020 for some populations.
Michael AP Bloomfield, Robert A McCutcheon ... Oliver Howes
Imaging and laboratory-induced psychosocial stress showed that exposure to psychosocial adversity was associated with dampened striatal dopaminergic function alongside blunted physiological yet potentiated subjective responses to acute stress.
Huan Song, Henrik Larsson ... Unnur A Valdimarsdóttir
A population-based analysis demonstrates that surviving twins who lose their co-twins by death are at considerably elevated risks of developing psychiatric disorders.
