81 results found
    1. Evolutionary Biology
    2. Genetics and Genomics

    The genetic factors of bilaterian evolution

    Peter Heger, Wen Zheng ... Thomas Wiehe
    Advanced orthology clustering of bilaterian and non-bilaterian sequences identifies 157 bilaterian-specific genes which are linked to key morphological features of this animal group.
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    Bayesian inference of kinetic schemes for ion channels by Kalman filtering

    Jan L Münch, Fabian Paul ... Klaus Benndorf
    For analyzing time-dependent patch-clamp or patch-clamp fluorometry data of ion channels in terms of Markovian models, the superiority of Bayesian filtering with respect to traditional deterministic approaches is demonstrated enabling more reliable quantification of the parameters.
    1. Genetics and Genomics
    2. Neuroscience

    A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes

    François Kroll, Gareth T Powell ... Jason Rihel
    Zebrafish knockouts can be generated in a few hours directly from wild-type eggs and are suitable for studying continuous traits, including behaviour.
    1. Neuroscience

    A theory of working memory without consciousness or sustained activity

    Darinka Trübutschek, Sébastien Marti ... Stanislas Dehaene
    Visual information can be maintained in non-conscious working memory for several seconds via short-term changes in synaptic weights.
    1. Neuroscience

    Brain signatures of a multiscale process of sequence learning in humans

    Maxime Maheu, Stanislas Dehaene, Florent Meyniel
    Evidence for multiple brain systems for sequence processing involving statistical inferences at multiple scales.
    1. Cell Biology
    2. Computational and Systems Biology

    From actin waves to mechanism and back: How theory aids biological understanding

    Carsten Beta, Leah Edelstein-Keshet ... Arik Yochelis
    Mathematical methods reveal common underlying principles in diverse models of intracellular actin waves.
    1. Neuroscience

    Catecholaminergic modulation of meta-learning

    Jennifer L Cook, Jennifer C Swart ... Roshan Cools
    A human psychopharmacology study reveals that a drug that affects the dopamine and noradrenaline systems enhances people's ability to adapt their learning rate to suit the volatility of the environment.
    1. Neuroscience

    The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle

    Carlos Manlio Díaz-García, Dylan J Meyer ... Gary Yellen
    When neurons are stimulated, calcium entry into mitochondria upregulates mitochondrial energy production, but glycolytic energy production in the cytosol is stimulated by elevated energy demand, not Ca2+ signaling.
    1. Neuroscience

    Methylphenidate enhances or impairs the cognitive control of Pavlovian bias depending on working memory capacity

    Dirk EM Geurts, Hanneke EM den Ouden ... Roshan Cools
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Physics of Living Systems

    Mechanically stimulated ATP release from murine bone cells is regulated by a balance of injury and repair

    Nicholas Mikolajewicz, Elizabeth A Zimmermann ... Svetlana V Komarova
    Bone cells exposed to physiological forces release ATP through repairable membrane injury, generating an intercellular signal that conveys the destructive potential of forces and the adaptive capacity of endangered cells.

Refine your results by:

Type
Research categories