The structures of plant CIII2, CIV, and SC III2+IV challenge long-standing assumptions, generate new mechanistic hypotheses and allow for the generation of more selective agricultural inhibitors.

The structure of the photosystem I (PSI) supercomplex in Ostreococcus tauri has revealed a unique hybrid of both plant-type and green algal-type PSI supercomplexes with three Lhcp trimers located at the ‘state 2’ position.

The nature of the phycobilisome–photosystem II supercomplex on the native thylakoid determined with cryo-electron tomography at an unprecedented resolution reveals that one phycobilisome interconnects with six photosystem monomers.

Inducing the formation of mitochondrial respiratory chain supercomplexes in Drosophila melanogaster, where they are normally absent, does not have any noticeable impact in the function of the respiratory chain.

PSD95 supercomplexes maintain long-term stability through gradual subunit replacement, with the slowest turnover in cortical synapses associated with memory storage.

Cryo-EM structure of the mammalian respiratory supercomplex containing complexes I, III and IV shows a functional asymmetry of complex III, providing strong evidence for directed electron flow in the respirasome.

The structure of the Mycobacterium smegmatis CIII₂CIV₂ respiratory supercomplex with telacebec (Q203) bound shows how this tuberculosis drug candidate blocks respiration in mycobacteria.

The molecular mechanisms of FCPI assembly and selective binding are revealed through comparison of PSI-FCPI structures in two diatom species.

Interleukin 6 (IL-6) can mediate pathogenesis of autoimmune diseases through its effects on mitochondrial function.

In situ cryo-electron tomography resolves individual photosynthetic complexes within native thylakoid membranes, revealing how thylakoid architecture sorts proteins into discrete membrane domains.