63 results found
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Genomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire ants

    Carlos Martinez-Ruiz, Rodrigo Pracana ... Yannick Wurm
    Analyses of allelic- and socially-biased gene expression reveal that suppressed recombination causes most of the expression differences in the social supergene, with only few differences due to socially antagonistic selection.
    1. Genetics and Genomics

    Dynamic molecular evolution of a supergene with suppressed recombination in white-throated sparrows

    Hyeonsoo Jeong, Nicole M Baran ... Soojin V Yi
    Comprehensive genomic and population genetic analyses of a non-recombining chromosome in white-throated sparrows reveal the actions of purifying selection, positive selection, and balancing selection, expanding our understanding of supergene evolution.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Epistatic selection on a selfish Segregation Distorter supergene – drive, recombination, and genetic load

    Beatriz Navarro-Dominguez, Ching-Ho Chang ... Amanda M Larracuente
    African haplotypes of a meiotic drive supergene in Drosophila melanogaster called Segregation Distorter show signs of a recent selective sweep, reduced recombination, and increased genetic load.
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Presence versus absence of CYP734A50 underlies the style-length dimorphism in primroses

    Cuong Nguyen Huu, Christian Kappel ... Michael Lenhard
    CYP734A50 is a heterostyly gene from primroses that underlies the differences in style length between the two forms by degrading growth-promoting hormones in the short styles.
    1. Evolutionary Biology

    Colour polymorphism associated with a gene duplication in male wood tiger moths

    Melanie N Brien, Anna Orteu ... Johanna Mappes
    A complex colour polymorphism which links colour with behavioural and life-history traits is associated with a single gene duplication in male wood tiger moths.
    1. Evolutionary Biology

    The genetic architecture of the load linked to dominant and recessive self-incompatibility alleles in Arabidopsis halleri and Arabidopsis lyrata

    Audrey Le Veve, Mathieu Genete ... Vincent Castric
    By modulating the intensity of balancing selection at the S-locus, dominance between self-incompatibility alleles shapes the genetic load linked to each allele, creating inbreeding depression in some S-locus homozygotes.
    1. Neuroscience
    2. Genetics and Genomics

    Regulatory changes in two chemoreceptor genes contribute to a Caenorhabditis elegans QTL for foraging behavior

    Joshua S Greene, May Dobosiewicz ... Cornelia I Bargmann
    A quantitative trait locus that includes two pheromone receptor genes affects foraging behavior; for one of the genes, the two alleles of the QTL have opposite effects because of distinct sites of expression.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Recognition and cleavage of human tRNA methyltransferase TRMT1 by the SARS-CoV-2 main protease

    Angel D'Oliviera, Xuhang Dai ... Jeffrey S Mugridge
    The SARS-CoV-2 main protease specifically cleaves a conserved sequence in the human tRNA modifying enzyme TRMT1, resulting in reduced tRNA binding and the complete loss of TRMT1-mediated tRNA methyltransferase activity.
    1. Genetics and Genomics

    An oligogenic architecture underlying ecological and reproductive divergence in sympatric populations

    Dušica Briševac, Carolina M Peralta, Tobias S Kaiser
    In the marine midge Clunio marinus, sympatric ecological population divergence with gene flow is based on at least four genetic loci, which partially overlap with large chromosomal inversions.

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