7,551 results found
  1. Meta-Research: Weak evidence of country- and institution-related status bias in the peer review of abstracts

    Mathias Wullum Nielsen et al.
    A preregistered survey experiment spanning six disciplines has found weak evidence of bias in favour of authors from high-status countries and institutions.
    1. Computational and Systems Biology
    2. Developmental Biology

    A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning

    Qixuan Wang et al.
    Regional differences in activator and inhibitor signals alter hair cycle pace across mouse skin and produce unique fur renewal 'landscapes', with fastest renewal on the ventrum and slowest renewal on the ear pinnae.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity

    Tamara M Sirey et al.
    Mitochondrial energy metabolism is post-transcriptionally regulated through an interplay between long and short non-coding RNAs.
    1. Neuroscience

    Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons

    Silvia Ripamonti et al.
    Perturbation of oxytocin signaling causes alterations that may be causally involved in the etiology of oxytocin-related neurobehavioral disorders.
    1. Neuroscience

    Aquaporin-4-dependent glymphatic solute transport in the rodent brain

    Humberto Mestre et al.
    An international collaboration between five independent research groups replicates findings confirming the importance of aquaporin-4 in glymphatic solute transport using five different mouse knockout lines.
    1. Cell Biology

    Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle

    Laurent Perrin et al.
    Rhythmic transcriptome analyses of human skeletal muscle tissue and cultured primary myotubes reveal an essential role for the circadian coordination of glucose homeostasis and lipid metabolism in human skeletal muscle.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Genetic and epigenetic variation in the lineage specification of regulatory T cells

    Aaron Arvey et al.
    There is limited epigenetic conservation of lineage-specific DNA elements in Treg cells, and genetic variation in Treg cell specific enhancers is associated with autoimmune disease.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h

    Nathan Gamarra et al.
    Auto-inhibition of ISWI-family ATP-dependent chromatin remodelers is relieved by a conserved feature of the nucleosome.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability

    Judith Schütte et al.
    A computer model built on insights gained from comprehensive experimental analysis reveals mechanisms of blood stem cell regulation.
    1. Neuroscience

    Human observers have optimal introspective access to perceptual processes even for visually masked stimuli

    Megan A K Peters, Hakwan Lau
    Despite the widely held belief among researchers in consciousness that healthy observers can show unconscious perception, a study using a novel method to control for response biases finds no evidence for this phenomenon.

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