3,783 results found
    1. Ecology
    2. Evolutionary Biology

    Intergenerational effects of early adversity on survival in wild baboons

    Matthew N Zipple et al.
    In wild baboons, a female's adverse early experiences can influence her offspring's survival years after the original adversity was experienced.
    1. Cell Biology
    2. Developmental Biology

    CasExpress reveals widespread and diverse patterns of cell survival of caspase-3 activation during development in vivo

    Austin Xun Ding et al.
    Genetic labeling of cells that survive executioner caspase activity in Drosophila reveals distinct patterns in different tissues.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Global divergence in critical income for adult and childhood survival: analyses of mortality using Michaelis–Menten

    Ryan J Hum et al.
    A mathematical model based on enzyme kinetics shows how the relationships between life expectancy, survival rates for children and adults, and national income change over time.
    1. Developmental Biology
    2. Neuroscience

    Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival

    Eleni Kougioumtzidou et al.
    Electrically active axons in white matter stimulate their own myelination by releasing glutamate, which signals through AMPA-type glutamate receptors on nearby oligodendrocyte precursors and newly-differentiating oligodendrocytes, enhancing their survival and hence their ability to myelinate.
    1. Neuroscience

    Localized hypoxia within the subgranular zone determines the early survival of newborn hippocampal granule cells

    Christina Chatzi et al.
    Neural progenitors reside in relative low oxygen in the subgranular zone (SGZ), and the higher tissue oxygen levels that these cells must face as they migrate away from the hypoxic areas and differentiate appear to cause oxidative damage and an early phase of cell death.
    1. Cell Biology
    2. Cancer Biology

    A kinase-independent function of AKT promotes cancer cell survival

    Igor Vivanco et al.
    The oncogenic potential of the serine threonine kinase AKT is not exclusively dependent on catalytic activity, but also involves the non-catalytic function of the pleckstrin homology domain.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The coordinated action of the MVB pathway and autophagy ensures cell survival during starvation

    Martin Müller et al.
    A catabolic cascade is essential to enter a stable G1/G0 quiescent state and survive extended periods of starvation.
    1. Cancer Biology
    2. Cell Biology

    Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism

    William Putzbach et al.
    Loading of CD95 and CD95L-derived sequences into the RNA-induced silencing complex elicits a distinct form of RNAi-mediated cell death of cancer cells that results from the targeting of multiple survival genes.
    1. Immunology and Inflammation
    2. Neuroscience

    Peripherally administered orexin improves survival of mice with endotoxin shock

    Yasuhiro Ogawa et al.
    When the neuropeptide orexin is peripherally administered in mice with septic shock, it penetrates the blood-brain barrier and acts in the brain to improve survival through multiple autonomic and neuroendocrine pathways.
    1. Microbiology and Infectious Disease

    Stochastic variation in the initial phase of bacterial infection predicts the probability of survival in D. melanogaster

    David Duneau et al.
    An analysis of within-host bacterial proliferation reveals that minor "stochastic" variation in the ability of the innate immune response to control bacterial growth early on can result in either survival or death of the host.

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