Unlike other taste modalities, the Drosophila taste system encodes salt taste combinatorially across multiple sensory neuron classes, which combine to produce behavioural valence and plasticity.

Drosophila larvae show taste multimodality and combinatorial sensing at gustatory organ level but also systemically as they employ complementary external and internal taste in sugar detection.

Taste-dependent satiation, which induces proper cessation of feeding in mammals as well as insects, is weakened by sugar-diet-driven taste impairment in the fruit fly.

The neural representation of perceived sucrose intensity was contained in the firing rate and spike-timing of a 'small' population of neurons distributed across the Insula and Orbitofrontal taste cortices.

Molecular-genetic, neural imaging and behavioral analyses reveal how Drosophila melanogaster sense fatty acids, important nutrient compounds, through multimeric Ionoptropic Receptors complexes.

Taste pathways to higher brain are critical for learned responses to taste compounds.

A single taste input, acetic acid, elicits opposing behavioral outputs depending on a fly's hunger state.

The Sip-Triggered Optogenetic Behavior Enclosure (STROBE) produces robust behaviors via activation of peripheral or central neurons in the fly, and mimics key features of feeding driven by chemical taste ligands.

A hyperpolarization-activated cation channel, counteracting membrane depolarization, delimits the excitability of receptor neurons subjected to naturally prolonged stimulation to preserve the function of neighboring receptor neurons in Drosophila gustation.

Bitter-sensing cells across different organs of the fruit fly activate overlapping neural pathways in the brain to regulate a common set of aversive behaviors.