226 results found
    1. Neuroscience

    Reinstatement of long-term memory following erasure of its behavioral and synaptic expression in Aplysia

    Shanping Chen et al.
    Storage of long-term memory in Aplysia does not require stable synapses.
    1. Neuroscience

    Energy efficient synaptic plasticity

    Ho Ling Li, Mark CW van Rossum
    The metabolic efficiency of learning in networks is improved by using forms of synaptic plasticity with different levels of persistence.
    1. Neuroscience

    Development of schemas revealed by prior experience and NMDA receptor knock-out

    George Dragoi, Susumu Tonegawa
    Novel spatial representations by hippocampal cellular assemblies develop on the framework of preconfigured hippocampal networks whose homeostatic synaptic reorganization is accelerated by prior experience and CA3 NMDAR-dependent plasticity.
    1. Neuroscience

    Role of protein synthesis and DNA methylation in the consolidation and maintenance of long-term memory in Aplysia

    Kaycey Pearce et al.
    Behavioral and synaptic investigations of long-term memory in Aplysia reveal differing roles for DNA methylation, protein synthesis during training and protein synthesis shortly after training with respect to memory consolidation and maintenance.
    1. Neuroscience

    Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amygdala

    Linnaea E Ostroff et al.
    A diverse assortment of mRNAs are present in projection axons in the adult forebrain and their translation is associated with new memory formation.
    1. Neuroscience

    Rotating waves during human sleep spindles organize global patterns of activity that repeat precisely through the night

    Lyle Muller et al.
    A phase-based analysis reveals wave-like spatiotemporal organization of the human sleep spindle, a brain oscillation critical to sleep-dependent memory consolidation, and elucidates its role in coordinating activity of neural networks distributed across the cortex.
    1. Neuroscience

    Can sleep protect memories from catastrophic forgetting?

    Oscar C González et al.
    Computational modeling predicts that sleep replay plays a protective role against catastrophic forgetting by revealing synaptic mechanisms allowing overlapping populations of neurons to store multiple interfering memories.
    1. Neuroscience

    Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1

    Robbert Havekes et al.
    The loss of neuronal connectivity in a brain region called the hippocampus significantly contributes to the cognitive impairments associated with sleep deprivation.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Satb2 determines miRNA expression and long-term memory in the adult central nervous system

    Clemens Jaitner et al.
    The genome-organizer Satb2 has a key role in memory formation by modulating availability of miRNAs that control the function of synapses.
    1. Neuroscience

    Impaired spatial memory codes in a mouse model of Rett syndrome

    Sara E Kee et al.
    Hypersynchrony in a mouse model of Rett syndrome impairs ripple-dependent memory consolidation and leads to a decrease in experience-dependent refinement of place cell activities.

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