890 results found
    1. Neuroscience

    Multimodal sensory integration in single cerebellar granule cells in vivo

    Taro Ishikawa et al.
    Building on previous work (Huang et al., 2013), it is shown that single granule cells receive excitatory synaptic input driven by up to three separate sensory modalities in vivo, which demonstrate that individual neurons can contribute to multisensory integration at the input layer of the cerebellar cortex.
    1. Neuroscience

    The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory

    Leanne J M Schmitz et al.
    Shisa7 is a bona-fide AMPAR modulatory protein affecting channel kinetics of hippocampal AMPARs, and is necessary for synaptic plasticity and memory recall.
    1. Neuroscience

    Synaptic representation of locomotion in single cerebellar granule cells

    Kate Powell et al.
    The first patch-clamp recordings from single cerebellar granule cells during locomotion reveal that the entire step sequence can be predicted from both excitatory synaptic input and output spikes from a single neuron.
    1. Neuroscience

    NG2 glial cells integrate synaptic input in global and dendritic calcium signals

    Wenjing Sun et al.
    NG2 glial cells respond to synaptic input with calcium signals in the absence of action potentials and process synaptic depolarizations with somatic and dendritic voltage gated channels.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Re-examining how complexin inhibits neurotransmitter release

    Thorsten Trimbuch et al.
    Challenging a widespread model, biophysical and electrophysiological experiments suggest a new mechanism whereby complexins inhibit neurotransmitter release through electrostatic repulsion between their accessory helix and the membranes.
    1. Neuroscience

    Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons

    Jegath C Athilingam et al.
    Serotonin changes passive membrane properties in prefrontal fast-spiking interneurons to affect not only neuronal excitability but also the temporal filtering of synaptic inputs with a preference for gamma-frequency summation.
    1. Developmental Biology

    The glycosphingolipid MacCer promotes synaptic bouton formation in Drosophila by interacting with Wnt

    Yan Huang et al.
    Multiple independent analyses reveal that a specific membrane lipid directly interacts with the signalling protein Wingless to promote synapse growth at the Drosophila neuromuscular junctions.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Molecular basis of sidekick-mediated cell-cell adhesion and specificity

    Kerry M Goodman et al.
    Crystal structures of synaptic recognition molecules Sidekick-1 and -2 reveal a single homodimer interaction mode responsible for both cell-cell recognition and cis-clustering, suggesting that competition between cis and trans interactions may be critical to specificity.
    1. Neuroscience

    Learning place cells, grid cells and invariances with excitatory and inhibitory plasticity

    Simon Nikolaus Weber, Henning Sprekeler
    A large variety of spatial representations implied in rodent navigation could arise robustly and rapidly from inputs with a weak spatial structure, by an interaction of excitatory and inhibitory synaptic plasticity.
    1. Neuroscience

    Somatostatin-positive interneurons in the dentate gyrus of mice provide local- and long-range septal synaptic inhibition

    Mei Yuan et al.
    Somatostatin-expressing interneurons of the rodent dentate gyrus fall into at least two functionally distinct interneuron types with different synaptic integrations into the local dentate gyrus and the more distant medial septum neuronal network.

Refine your results by:

Type
Research categories