18 results found
    1. Cell Biology
    2. Developmental Biology

    R-spondins can potentiate WNT signaling without LGRs

    Andres M Lebensohn, Rajat Rohatgi
    R-spondins 2 and 3 can potentiate WNT signaling in the absence of LGRs through interactions with ZNRF3/RNF43 E3 ubiquitin ligases and heparan sulfate proteoglycans, defining two alternative modes of R-spondin-mediated signaling.
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium

    David R Hill et al.
    Contact with bacteria and subsequent hypoxia promotes functional maturation of the immature gastrointestinal tract.
    1. Neuroscience

    Tracing neuronal circuits in transgenic animals by transneuronal control of transcription (TRACT)

    Ting-hao Huang et al.
    A new method that will allow researchers to visualize and genetically manipulate synaptically connected neurons in a brain circuit.
    1. Cell Biology
    2. Neuroscience

    Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction

    Qi Wang et al.
    Characterization of Tnc as a selective integrin ligand at the Drosophila NMJ allows for unprecedented insights into our understanding of extracellular matrix/integrin interactions at synaptic locations and reveals novel, distinct presynaptic and postsynaptic integrin functions.
    1. Neuroscience

    A dystonia-like movement disorder with brain and spinal neuronal defects is caused by mutation of the mouse laminin β1 subunit, Lamb1

    Yi Bessie Liu et al.
    A mouse with a defined mutation in an extracellular matrix protein that is expressed in selected neurons sheds light on circuit abnormalities producing transient hyperkinetic movements.
    1. Developmental Biology
    2. Neuroscience

    Cis and trans RET signaling control the survival and central projection growth of rapidly adapting mechanoreceptors

    Michael S Fleming et al.
    Cis and trans activation of the receptor tyrosine kinase RET lead to similar biological outcomes in rapidly adapting mechanoreceptors in vivo.
    1. Neuroscience

    An insect-like mushroom body in a crustacean brain

    Gabriella Hannah Wolff et al.
    An insect-like mushroom body in one group of crustaceans, the mantis shrimps (Stomatopoda), suggests either an ancient origin of this center and its reduction and loss in other crustaceans, or an extraordinary example of convergent evolution with the insect mushroom body.
    1. Developmental Biology

    Dual control of pcdh8l/PCNS expression and function in Xenopus laevis neural crest cells by adam13/33 via the transcription factors tfap2α and arid3a

    Vikram Khedgikar et al.
    The regulation of tfap2α expression by adam13 is essential during cranial neural crest cell migration in Xenopus laevis.
    1. Neuroscience

    The functional organization of descending sensory-motor pathways in Drosophila

    Shigehiro Namiki et al.
    Systematic analysis of descending neuron anatomy reveals the basic functional map of descending sensory-motor pathways in flies and provides genetic tools for targeted interrogation of neural circuits.
    1. Developmental Biology

    Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates

    Michael W Susman et al.
    Kif26b, a new component of the evolutionarily conserved Wnt5a-Ror signaling pathway, is controlled by regulated proteolysis and plays crucial roles in mediating vertebrate embryonic tissue morphogenesis.

Refine your results by:

Type
Research categories