A synthetic quadrastable gene network provides a synthetic biology framework to study cell fate determination.

Perturbations in the extracellular environment drive transitions from a highly stable memory state to an alternative phenotype in microorganisms.

Stem cell derived ventral-spinal cord excitatory neurons self-assemble into a rhythmically bursting neural network whose speed and intercellular coordination are both instructively modulated by cell-type specific interactions with inhibitory neurons.

Network architecture and physiological features of the cell dictate asymmetric gene regulation between a negative autoregulatory TF gene and its target gene.

Rapid forward engineering can be accomplished using cell-free systems, as demonstrated by the implementation and characterization of novel genetic oscillators in a cell-free system and their consequent transfer to cells.

Analysis of experiments on bacteria suggests that the dependence of cell size on growth rate is not an adaptation but a causal consequence of a regulatory mechanism that controls DNA replication.

The life cycle and morphology of the sea squirt Ciona intestinalis shed light on vertebrate evolution.

Drugs called bisphosphonates are used to treat a range of bone diseases, but how do they reach the enzymes that are their target?