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Circulating immune cells reflect intra-tumoural immunity and can predict response to systemic therapy in head and neck cancer.

A detailed characterizations of EDTA-treated Candida albicans cells both in vitro and pre-clinical models led to discovery of a potential live whole-cell vaccine against fungal infections.

Expression of plant immune genes is controlled by the opposing actions of ubiquitin ligases and deubiquitinases that modify the master coactivator NPR1, thereby regulating its intrinsic transcriptional activity.

Parasite variants associated with severe malaria do not have an intrinsic growth or survival advantage in vivo, which indicates that a change in host environment is required for their selection.

Activated Drosophila macrophages undergo transient metabolic remodeling towards Hypoxia inducible factor 1 α-driven aerobic glycolysis, a program that induces systemic metabolic changes and is crucial for resistance to infection.

Alteration of host gut microbiota by antibiotic exposure in early life remodeled host intestinal immune development and metabolism and enhanced the induction of type 1 diabetes in genetically predisposed animals.

A viral protein hijacks the key effector of transcriptional gene silencing, Su(var)3-9, to evade host plant surveillance.

The Reproducibility for Everyone initiative aims to provide researchers at all career stages and across many disciplines with training in reproducible research practices via customizable workshop material.

Natural antibodies play a fundamental role in anti-cancer immunity.

The horizontal acquisition of virulence plasmids is potentiated by production practices in plant nurseries and is sufficient to transition Rhodococcus from being beneficial to being pathogenic.