5,730 results found
    1. Stem Cells and Regenerative Medicine
    2. Developmental Biology

    Hair follicle epidermal stem cells define a niche for tactile sensation

    Chun-Chun Cheng et al.
    Heterogeneous epidermal stem cells define a niche for tactile sensation via providing a unique ECM and tissue architecture for nerves, revealing their new functions in coordinated sensory organ formation.
    1. Stem Cells and Regenerative Medicine
    2. Chromosomes and Gene Expression

    Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency

    Yul W Yang et al.
    RNA binding is a key input of an active chromatin complex and maintenance of stem cell fate.
    1. Neuroscience

    Tactile sensory channels over-ruled by frequency decoding system that utilizes spike pattern regardless of receptor type

    Ingvars Birznieks et al.
    Perception of vibrotactile frequency depends on the neural discharge pattern rather than the afferent type, thus requiring a reevaluation of the notion of Pacinian/non-Pacinian channels in tactile sensory system.
    1. Neuroscience

    Neuroscience: How keeping active pays off in the olfactory system

    Kevin Monahan, Stavros Lomvardas
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    1. Cell Biology
    2. Neuroscience

    Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells

    Matthew J Sternfeld et al.
    Stem cell derived ventral-spinal cord excitatory neurons self-assemble into a rhythmically bursting neural network whose speed and intercellular coordination are both instructively modulated by cell-type specific interactions with inhibitory neurons.
    1. Neuroscience

    A robust activity marking system for exploring active neuronal ensembles

    Andreas T Sørensen et al.
    A new system for tagging activated neuronal population offers multiple advantages over existing systems based on immediate early genes, including greater sensitivity and specificity, and suitability for easy application in species other than mice.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Compaction and segregation of sister chromatids via active loop extrusion

    Anton Goloborodko et al.
    Loop extrusion can robustly compact, segregate and disentangle mammalian chromosomes, suggesting it is a universal mechanism of genome folding during cell division.
    1. Chromosomes and Gene Expression

    Non-canonical TAF complexes regulate active promoters in human embryonic stem cells

    Glenn A Maston et al.
    The transcription machinery used to regulate gene expression and self-renewal in human embryonic stem cells is different from that found in other cells.
    1. Neuroscience

    Fast and accurate edge orientation processing during object manipulation

    J Andrew Pruszynski et al.
    Tactile edge orientation processing during object manipulation is many times better than previously thought based on perceptual studies.
    1. Developmental Biology
    2. Plant Biology

    Integration of light and metabolic signals for stem cell activation at the shoot apical meristem

    Anne Pfeiffer et al.
    TOR kinase guides the transition of plant stem cells from the dormant embryonic state to the active adult state by integrating light and metabolic signals.

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