Novel imaging experiments suggest that fruit flies modify their neural circuitry for walking at slow, medium and fast speeds, and that proprioception is not essential for coordinated walking.
Carmela Sidrauski, Diego Acosta-Alvear ... Peter Walter
A compound that prevents stressors such as UV light and viral infection from downregulating protein synthesis inside cells improves memory performance in mice.
A normally cytoplasmic deacetylase, Hdac6, localizes to the nucleus in embryonic stem cells, where it regulates the essential Tip60-p400 chromatin remodeling complex.
A combination of phylogenetic and biochemical analyses suggest that some unexpected variations in the synthesis of isoprenoids may be widespread across all three domains of life.
Shigeyuki Tanaka, Thomas Brefort ... Regine Kahmann
A fungal effector secreted by the corn smut pathogen increases the virulence of the pathogen by elevating anthocyanin production and reducing lignification in maize.
Lab-evolved 'super Spy' chaperones show enhanced flexibility, which allows them to bind to and stabilize proteins more effectively than natural chaperones.
The repair of spontaneous DNA damage can introduce mutators that lead to further genetic changes, which could underlie evolutionary change, disease and aging.