3,810 results found
    1. Medicine
    2. Neuroscience

    mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

    Philip Stavrides, Chris N Goulbourne ... Dun-Sheng Yang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome

    Rohan Eapen, Cynthia Okoye ... Laura S Itzhaki
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology

    Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling

    Giuliana Giamundo, Daniela Intartaglia ... Ivan Conte
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Cancer Biology

    Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer

    Jessica Armand, Sungsoo Kim ... Hee Won Yang
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Cancer Biology

    Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis

    Zuzana Outla, Gizem Oyman-Eyrilmez ... Martin Gregor
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience
    2. Physics of Living Systems

    A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy

    Matthew Rozak, James Mester ... Bojana Stefanovic
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Decoding the physics of observed actions in the human brain

    Moritz F Wurm, Doruk Yiğit Erigüç
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics

    Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes

    Shuai Zhang, Ruixue Wang ... Lin Sun
    Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m6A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.
    1. Biochemistry and Chemical Biology

    Induction of Hepatitis B Core Protein Aggregation Targeting an Unconventional Binding Site

    Vladimir Khayenko, Cihan Makbul ... Hans M Maric
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    PAbFold: Linear Antibody Epitope Prediction using AlphaFold2

    Jacob DeRoo, James S Terry ... Brian J Geiss
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete

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