230 results found
    1. Neuroscience

    Sucrose intensity coding and decision-making in rat gustatory cortices

    Esmeralda Fonseca, Victor de Lafuente ... Ranier Gutierrez
    The neural representation of perceived sucrose intensity was contained in the firing rate and spike-timing of a 'small' population of neurons distributed across the Insula and Orbitofrontal taste cortices.
    1. Neuroscience

    Selective integration of diverse taste inputs within a single taste modality

    Julia U Deere, Arvin A Sarkissian ... Anita V Devineni
    Bitter-sensing cells across different organs of the fruit fly activate overlapping neural pathways in the brain to regulate a common set of aversive behaviors.
    1. Neuroscience

    Functional brain reconfiguration during sustained pain

    Jae-Joong Lee, Sungwoo Lee ... Choong-Wan Woo
    Human neuroimaging with time-evolving network analysis reveals dynamic interactions among multiple functional brain networks in response to sustained pain.
    1. Evolutionary Biology
    2. Medicine

    Taste shaped the use of botanical drugs

    Marco Leonti, Joanna Baker ... Julie Hawkins
    Plant drugs used by ancient Graeco-Roman societies have tastes and flavours that predict how they were used therapeutically.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Chloride ions evoke taste sensations by binding to the extracellular ligand-binding domain of sweet/umami taste receptors

    Nanako Atsumi, Keiko Yasumatsu ... Atsuko Yamashita
    Sweet and umami taste receptors are capable of sensing chloride ions, a component of table salt other than the salty taste-inducing component, sodium ions, and induce preferable taste sensations such as sweet taste.
    1. Neuroscience

    Ir56d-dependent fatty acid responses in Drosophila uncover taste discrimination between different classes of fatty acids

    Elizabeth B Brown, Kreesha D Shah ... Alex C Keene
    The taste system of fruit flies is activated by broad classes of fatty acids and can discriminate between different classes, revealing previously underappreciated complexity in the coding of tastants.
    1. Neuroscience

    Closed-loop optogenetic activation of peripheral or central neurons modulates feeding in freely moving Drosophila

    Pierre-Yves Musso, Pierre Junca ... Michael D Gordon
    The Sip-Triggered Optogenetic Behavior Enclosure (STROBE) produces robust behaviors via activation of peripheral or central neurons in the fly, and mimics key features of feeding driven by chemical taste ligands.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function

    Erin J Golden, Eric D Larson ... Linda A Barlow
    Taste cell renewal begins at birth and is promoted by sonic hedgehog that alters the expression of regulators of cell migration and adhesion that may allow entry of new cells into buds.
    1. Neuroscience

    Adaptation of Drosophila larva foraging in response to changes in food resources

    Marina E Wosniack, Dylan Festa ... Jimena Berni
    Drosophila larvae foraging adapt to different food quality and distributions modulating specific motor programs, as revealed by behavioral and modeling experiments.
    1. Neuroscience

    Molecular basis of fatty acid taste in Drosophila

    Ji-Eun Ahn, Yan Chen, Hubert Amrein
    Molecular-genetic, neural imaging and behavioral analyses reveal how Drosophila melanogaster sense fatty acids, important nutrient compounds, through multimeric Ionoptropic Receptors complexes.

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