370 results found
    1. Neuroscience

    Bitter taste receptors confer diverse functions to neurons

    Rebecca Delventhal, John R Carlson
    Expression of Drosophila bitter receptors in taste neurons produced increased, decreased, or novel responses, supporting a model in which the response profile is determined by activation, inhibition, or competition among receptors.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    A receptor and neuron that activate a circuit limiting sucrose consumption

    Ryan M Joseph et al.
    Although sugar-sensing taste neurons typically promote feeding, a taste neuron in the Drosophila pharynx limits feeding via the IR60b receptor; thus, revealing a new element in the circuit logic of feeding control.
    1. Neuroscience

    Molecular basis of fatty acid taste in Drosophila

    Ji-Eun Ahn et al.
    Molecular-genetic, neural imaging and behavioral analyses reveal how Drosophila melanogaster sense fatty acids, important nutrient compounds, through multimeric Ionoptropic Receptors complexes.
    1. Neuroscience

    Evolutionary shifts in taste coding in the fruit pest Drosophila suzukii

    Hany KM Dweck et al.
    The evolutionary transition of the agricultural pest Drosophila suzukii to egg laying on ripe fruits was paralleled with several gustatory innovations.
    1. Neuroscience

    Internal amino acid state modulates yeast taste neurons to support protein homeostasis in Drosophila

    Kathrin Steck et al.
    Two different classes of taste receptor neurons in the Drosophila melanogaster proboscis play distinct roles in yeast feeding and are both modulated by the fly's internal amino acid state in order to promote protein-specific appetite.
    1. Ecology

    A gustatory receptor tuned to the steroid plant hormone brassinolide in Plutella xylostella (Lepidoptera: Plutellidae)

    Ke Yang et al.
    The gustatory receptor PxylGr34 is tuned to the steroid plant hormone brassinolide and mediates the deterrent effects of brassinolide on feeding and ovipositing behaviors in Plutella xylostella.
    1. Neuroscience

    A complex peripheral code for salt taste in Drosophila

    Alexandria H Jaeger et al.
    Unlike other taste modalities, the Drosophila taste system encodes salt taste combinatorially across multiple sensory neuron classes, which combine to produce behavioural valence and plasticity.
    1. Neuroscience

    Ir56d-dependent fatty acid responses in Drosophila uncover taste discrimination between different classes of fatty acids

    Elizabeth B Brown et al.
    The taste system of fruit flies is activated by broad classes of fatty acids and can discriminate between different classes, revealing previously underappreciated complexity in the coding of tastants.
    1. Neuroscience

    Insula to mPFC reciprocal connectivity differentially underlies novel taste neophobic response and learning in mice

    Haneen Kayyal et al.
    aIC to mPFC connections are correlative and necessary both for taste novelty behavior and learning while the reciprocal connection from mPFC to aIC is correlative and necessary for novelty behavior.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein

    Javier García-Nafría et al.
    The adenosine A2a receptor couples to the heterotrimeric G protein Gs using both conserved contacts seen in other complexes and, in addition, novel contacts to the beta subunit of the G protein.

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