20 results found
    1. Developmental Biology

    MicroRNA-934 is a novel primate-specific small non-coding RNA with neurogenic function during early development

    Kanella Prodromidou et al.
    Primate-specific miR-934 mediates neurogenesis and downstream neuronal differentiation processes, modulating the expression of genes associated with the subplate, a region most prominent in primates, emerging during early cortical development.
    1. Developmental Biology
    2. Neuroscience

    MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex

    Wei Zhang et al.
    During early cortical development, microRNA-128 regulates the homeostasis of neural stem cells by targeting PCM1, a protein that is critical for cell division.
    1. Developmental Biology
    2. Neuroscience

    Intermediate progenitors support migration of neural stem cells into dentate gyrus outer neurogenic niches

    Branden R Nelson et al.
    Multiphoton live-imaging illuminates the dynamic underpinnings of how different types of progenitor cells migrate and interact to robustly build the mammalian Dentate Gyrus neural circuitry and new outer neurogenic niche.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

    Madeline G Andrews et al.
    mTOR signaling regulates the morphology of a human-enriched neural stem cell population and thus contributes to the radial architecture of the developing human cortex with implications for neurodevelopmental disease.
    1. Developmental Biology
    2. Neuroscience

    Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex

    Ayse Güven et al.
    Transcription factor Sox9 has an important role in neocortex expansion, where its expression in basal progenitors increases proliferation, induces premature gliogenesis and promotes the expression of extracellular matrix components.
    1. Developmental Biology

    Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis

    Shauna L Houlihan et al.
    Analyses based on the mouse model of a human genetic disease reveal that the neuron production of cerebral tissue can be boosted by escalated signaling between neural progenitors and the vasculature.
    1. Computational and Systems Biology
    2. Developmental Biology

    Discovering sparse transcription factor codes for cell states and state transitions during development

    Leon A Furchtgott et al.
    Sparse patterns in gene expression allow simultaneous discovery of cell states, lineage relationships and key genes controlling developmental decisions.
    1. Developmental Biology
    2. Neuroscience

    A stochastic framework of neurogenesis underlies the assembly of neocortical cytoarchitecture

    Alfredo Llorca et al.
    The specification of a very small number of progenitor cells with competence to adapt their neurogenic output to different probabilistic rules underlies the generation of distinct cortical cytoarchitectures.
    1. Developmental Biology
    2. Neuroscience

    Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia

    Xin Heng et al.
    Genome-wide transcriptional profiling and genetic analyses reveal conserved mechanisms underlying the generation of neocortical basal radial glia and cerebellar Bergmann glia.
    1. Neuroscience

    A cell atlas of the chick retina based on single-cell transcriptomics

    Masahito Yamagata et al.
    A molecular atlas of the chick retina provides a comprehensive classification and characterization of 136 cell types, yielding novel insights into retinal structure, function, development, and evolution.

Refine your results by:

Type
Research categories