Telomere length distributions can be used to infer important properties of stem cell proliferation.

Human telomerase unfolds and extends parallel G-quadruplexes using a unique mechanism involving its RNA template.

Genetic predisposition to uterine leiomyomas arises from variation at loci for genetic stability and genitourinary development, and in part explains the frequent occurrence of the condition in women with African origin.

In yeast, the secondary pathway for recruiting telomerase to chromosome ends requires a component of telomeric transcriptionally silent chromatin.

The Cajal body chaperone TCAB1 and scaffold protein Coilin are not required for telomerase activity in human cells.

Previously uncharacterized long repeat sequences are associated with significant genome variation that can increase fitness and promote antifungal drug resistance in diverse isolates of Candida albicans.

An efficient response to DNA damage requires the assembly of actin filaments in the nucleus.

In contrast with earlier conclusions, negative selection has a major role in cancer evolution.

Cooperative association of a histone-binding complex with pairs of appropriately modified nucleosomes, which form fundamental units of binding, mediates selective heterochromatin assembly and spreading.