Browse the search results

Page 2 of 22
    1. Chromosomes and Gene Expression

    Telomere repeats induce domains of H3K27 methylation in Neurospora

    Kirsty Jamieson et al.
    Vast regions of facultative heterochromatin marked by methylation of lysine 27 on histone H3 depend on their proximity to chromosome ends and can be induced ectopically by insertion of telomere repeats.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Oncogenesis: Taking the brakes off telomerase

    Kamila Naxerova, Stephen J Elledge
    Insight
    Available as:
    • HTML
    • PDF
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Cancer-associated TERT promoter mutations abrogate telomerase silencing

    Kunitoshi Chiba et al.
    TERT promoter mutations impair TERT silencing upon cellular differentiation and are sufficient to facilitate cellular immortalization without additional tumor selected changes, explaining why they are associated with a very specific tumor spectrum.
    1. Chromosomes and Gene Expression

    Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria

    Alexandre Chojnowski et al.
    Expression of the lamina-associated polypeptide α (LAP2α) prevents premature cellular ageing caused by expression of progerin in Hutchinson-Gilford progeria syndrome.
    1. Neuroscience

    Oxytocin-mediated social enrichment promotes longer telomeres and novelty seeking

    Jamshid Faraji et al.
    Social enrichment supports longevity.
    1. Chromosomes and Gene Expression
    2. Stem Cells and Regenerative Medicine

    TERRA regulate the transcriptional landscape of pluripotent cells through TRF1-dependent recruitment of PRC2

    Rosa María Marión et al.
    Telomeric TRF1 controls the transcriptional programmes of pluripotent stem cells by recruiting PRC2 to pluripotency and differentiation genes by controlling the expression of those gene sites and the binding of TERRA RNAs to them.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation

    Rebecca Devlin et al.
    Mapping DNA replication timing, allied to genetic analysis of a RecQ repair helicase, reveals that antigenic variation in the African trypanosome may be initiated by locus-specific, replication-derived sequence instability.
    1. Neuroscience

    Social Neuroscience: How does social enrichment produce health benefits?

    Takefumi Kikusui
    Oxytocin appears to link social interaction and cell aging in rats, especially in females.
    Insight
    Available as:
    • HTML
    • PDF
    1. Developmental Biology
    2. Evolutionary Biology

    Research: Titles and abstracts of scientific reports ignore variation among species

    Barbara R Migeon
    Ignoring the probability of species variation when reporting observations about biological processes leads to misinterpretation of the experimental data.