242 results found
    1. Neuroscience

    Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons

    Jegath C Athilingam et al.
    Serotonin changes passive membrane properties in prefrontal fast-spiking interneurons to affect not only neuronal excitability but also the temporal filtering of synaptic inputs with a preference for gamma-frequency summation.
    1. Neuroscience

    Biophysics of object segmentation in a collision-detecting neuron

    Richard Burkett Dewell, Fabrizio Gabbiani
    Active dendritic processing enables an individual neuron to discriminate the spatial pattern of synaptic inputs, increasing neural and behavioral selectivity for escaping an impending threat.
    1. Neuroscience

    Retinal direction selectivity in the absence of asymmetric starburst amacrine cell responses

    Laura Hanson et al.
    Experimental and computational models reveal how parallel 'core' mechanisms shape direction selectivity at the dendrites of starburst amacrine cells and ganglion cells in the mouse retina.
    1. Neuroscience

    Synaptic representation of locomotion in single cerebellar granule cells

    Kate Powell et al.
    The first patch-clamp recordings from single cerebellar granule cells during locomotion reveal that the entire step sequence can be predicted from both excitatory synaptic input and output spikes from a single neuron.
    1. Neuroscience

    The computation of directional selectivity in the Drosophila OFF motion pathway

    Eyal Gruntman et al.
    ON and OFF visual motion is computed with the same algorithm despite differences in circuit architecture.
    1. Computational and Systems Biology
    2. Neuroscience

    Mapping nonlinear receptive field structure in primate retina at single cone resolution

    Jeremy Freeman et al.
    Multi-electrode recordings and modeling are combined to reveal the transformations of signals from cones to bipolar cells and then to ganglion cells within the primate retina.
    1. Neuroscience

    A simple retinal mechanism contributes to perceptual interactions between rod- and cone-mediated responses in primates

    William N Grimes et al.
    A combination of physiological and perceptual experiments show that the responses of rod photoreceptors inhibit those of cones more than vice versa, and reveal both the site of the retinal interaction and the underlying mechanism.
    1. Neuroscience

    Feed-forward recruitment of electrical synapses enhances synchronous spiking in the mouse cerebellar cortex

    Andreas Hoehne et al.
    Transient recruitment of electrical synapses mediates precisely timed excitation and inhibition to enhance synchronized control of cerebellar cortical output.
    1. Neuroscience

    NMDA spikes mediate amplification of inputs in the rat piriform cortex

    Amit Kumar et al.
    Dendrites of pyramidal neurons in piriform cortex can initiate NMDA spikes, which may serve to amplify odor responses, and provide combination selectivity underlying 'discontinuous' odor receptive fields in these neurons.
    1. Neuroscience

    A cellular mechanism for inverse effectiveness in multisensory integration

    Torrey LS Truszkowski et al.
    Building on previous work (Felch et al., 2016), it is shown that inverse effectiveness, a central property of multisensory integration, in the optic tectum is mediated by the activation of NMDA-type glutamate receptors, resulting in a response greater than the sum of responses to each individual sensory modality.

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