Reward and information are independently optimized in the human prefrontal cortex, while their signals combine in subcortical regions.

Investigation of the role of triple-stranded nucleic acid, R-loops, in HIV-1 genome integration.

Methods for screening hundreds of DNA sequences for enhancer activity have been extended for use in vivo, uncovering novel enhancer elements active in the early postnatal brain.

Distance-based TCR analysis enables grouping of biochemically similar clonotypes into meta-clonotypes that have increased publicity, and therefore statistical power, for population-level detection of antigen-specific T cells in infection and vaccination.

Heterochromatin is established at nucleation sites associated with open chromatin and RNA transcripts and matures into stable domains if they are found near transposable elements targeted by maternally deposited piRNAs.

Transsynaptic viral tracing reveals that neurons in the superior colliculus employ projection specific rules to the sampling of retinal inputs, directing distinct visual features to different downstream targets.

The Botryllus schlosseri genome yields insights into the evolution of hematopoiesis.

Chick optic fissure closure is a powerful new model system for epithelial fusion and has revealed Netrin-1 as a conserved and essential mediator of tissue fusion in multiple contexts.

Astrocytic G_i pathway activation in the anterior cingulate cortex impairs schema memory and neuronal mitochondrial biogenesis, which can be rescued by exogenous L-lactate administration directly into the area.

The glycinergic neurons of the cerebellar nuclei project extensively to the cerebellar cortex and inhibit GABAergic Golgi cells.