3,654 results found
    1. Developmental Biology
    2. Neuroscience

    A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life

    Weidong Feng et al.
    A molecular mechanism that involves highly conserved transcription factors enables cholinergic motor neurons of the nematode Caenorhabditis elegans to become and remain functional.
    1. Developmental Biology

    Mamo decodes hierarchical temporal gradients into terminal neuronal fate

    Ling-Yu Liu et al.
    Neuronal diversity is expanded by a temporal fating paradigm utilizing hierarchical gene regulation.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Point of View: Is cell size a spandrel?

    Ariel Amir
    Analysis of experiments on bacteria suggests that the dependence of cell size on growth rate is not an adaptation but a causal consequence of a regulatory mechanism that controls DNA replication.
    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic et al.
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.
    1. Microbiology and Infectious Disease

    HIV in Women: How HIV exploits T cells in the endometrium

    Marta Rodriguez-Garcia
    Immune cells in the endometrium are targeted by HIV and re-programmed to allow them to survive and spread the virus throughout the body.
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    1. Neuroscience

    Mating Behaviour: To mate or not to mate

    Florencia Campetella, Silke Sachse
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    1. Cell Biology
    2. Developmental Biology

    Philosophy of Biology: The analysis of living systems can generate both knowledge and illusions

    Antony M Jose
    By thinking about experimental techniques in terms of six broad approaches – perturbation, visualization, substitution, characterization, reconstitution, and simulation – researchers may be able to generate more reliable inferences.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Aging: A new defense in the battle of the sexes

    George L Sutphin
    Young Caenorhabditis elegans hermaphrodites use their own sperm to protect against the negative consequences of mating.
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