Newly formed tetraploid cells rapidly lose extra centrosomes acquired upon tetraploidization via asymmetric centrosome clustering during cell division and selective advantage of tetraploid daughter cells that inherit a single centrosome.

A ménàge à trois introduces extra DNA only to plant embryos, thus skipping endosperm-induced seed hybridization barriers.

Mitochondrial fusion enables a metabolic transition during spermatogenesis.

The protozoan parasite Trypanosoma brucei gambiense has undergone recent clonal evolution that reveals the theoretically predicted Meselson effect at a genome-wide level.

Aneuploidy can cause chromosome mis-segregation and specific cellular phenotypes driven by expression of genes on the extra chromosome.

Terminally differentiated neurons and glia can re-enter the cell cycle to become polyploid in the adult fly brain, to protect cells from DNA damage-associated death.

Post-implantation epiblast maturation and patterning of anterior-posterior axis in mouse embryonic development are mediated by pluripotency transcription factor Zfp281 through transcriptional and epigenetic control of Nodal signaling.

Dosage-compensated gene expression facilitates chromosomal aneuploidy, which presents a rapid route to phenotypic evolution in natural yeast isolates.

The retinoblastoma tumor suppressor regulates cell cycle progression when it's in 14 mono-phosphorylated isoforms.

The genome sequence of Trichoplusia ni enables the use of this widespread lepidopteran pest as a model for both the study of small RNA pathways and insecticide resistance.