1,026 results found
    1. Neuroscience

    Robotic multi-probe single-actuator inchworm neural microdrive

    Richard D Smith, Ilya Kolb ... Mladen Barbic
    A novel micropositioning approach allows remote-controlled, micrometer-resolution actuation of many densely packed, arbitrarily shaped probes with a device whose size and weight scale much more efficiently with probe count compared to current methods.
    1. Neuroscience

    Differences in reward biased spatial representations in the lateral septum and hippocampus

    Hannah S Wirtshafter, Matthew A Wilson
    Reward-related spatial information is preferentially represented in the lateral septum compared to the hippocampus and may be used downstream to direct the animal to rewarded locations.
    1. Genetics and Genomics
    2. Plant Biology

    The genomic landscape of meiotic crossovers and gene conversions in Arabidopsis thaliana

    Erik Wijnker, Geo Velikkakam James ... Korbinian Schneeberger
    A comprehensive and genome-wide description of the genomic make-up and frequency of meiotic recombination in Arabidopsis thaliana reveals regional preferences, including nucleosome-free regions, and two associated recombination motifs.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus

    Michael Habig, Gert HJ Kema, Eva Holtgrewe Stukenbrock
    Female-inherited supernumerary chromosomes that lack a male-inherited homolog are transmitted to all meiotic products instead of the expected half, which indicates an additional amplification of unpaired chromosomes during meiosis.
    1. Neuroscience

    Mesotrode allows chronic simultaneous mesoscale cortical imaging and subcortical or peripheral nerve spiking activity recording in mice

    Dongsheng Xiao, Yuhao Yan, Timothy H Murphy
    Low-profile tetrodes that are compatible with wide-field imaging provide the opportunity to evaluate the relationship between spiking neurons and broad networks.
    1. Neuroscience

    Automated long-term recording and analysis of neural activity in behaving animals

    Ashesh K Dhawale, Rajesh Poddar ... Bence P Ölveczky
    A new automated system for recording and analyzing neural activity in behaving animals over months-long time-scales offers new perspectives on how neural circuits underlie processes such as learning, development, and recovery from brain injury.
    1. Neuroscience

    Interpreting wide-band neural activity using convolutional neural networks

    Markus Frey, Sander Tanni ... Caswell Barry
    A novel deep-learning framework shows how to interpret and decode raw neural recordings, avoiding the need for strong prior hypotheses, revealing a novel representation of head direction.
    1. Neuroscience

    Coordinated head direction representations in mouse anterodorsal thalamic nucleus and retrosplenial cortex

    Marie-Sophie H van der Goes, Jakob Voigts ... Mark T Harnett
    Dual site recordings of mouse anterodorsal thalamic nucleus and retrosplenial cortex reveal near 0-ms lag between the head direction representations of the two regions after cue rotations and correlated drift in darkness.
    1. Neuroscience

    Visual landmarks sharpen grid cell metric and confer context specificity to neurons of the medial entorhinal cortex

    José Antonio Pérez-Escobar, Olga Kornienko ... Kevin Allen
    The firing rate of MEC neurons conveys information about visual landmarks.
    1. Neuroscience

    Arcuate hypothalamic AgRP and putative POMC neurons show opposite changes in spiking across multiple timescales

    Yael Mandelblat-Cerf, Rohan N Ramesh ... Mark L Andermann
    Gradual changes in the firing of specific hypothalamic neurons over many hours signal falling energy levels, while short-lived changes over seconds and minutes signal the availability of food.

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