1,099 results found
    1. Neuroscience

    Multiple decisions about one object involve parallel sensory acquisition but time-multiplexed evidence incorporation

    Yul HR Kang, Anne Löffler ... Michael N Shadlen
    When making two decisions about one object, two streams of information can be acquired in parallel but must be incorporated into the two decisions serially, consistent with a central bottleneck.
    1. Neuroscience

    Effects of clozapine-N-oxide and compound 21 on sleep in laboratory mice

    Janine Traut, Jose Prius Mengual ... Lukas B Krone
    The two most commonly used chemogenetic actuators, clozapine-N-oxide and compound 21, similarly modulate sleep in wild-type laboratory mice indicating that even designer drugs which do not convert to clozapine can elicit behavioural effects and require adequate controls.
    1. Neuroscience

    A prefrontal network model operating near steady and oscillatory states links spike desynchronization and synaptic deficits in schizophrenia

    David A Crowe, Andrew Willow ... Bagrat Amirikian
    Cortical network model suggests a mechanism explaining the link between NMDAR synaptic and spike synchrony deficits observed in a pharmacological monkey model of prefrontal network failure in schizophrenia.
    1. Neuroscience

    The effects of chloride dynamics on substantia nigra pars reticulata responses to pallidal and striatal inputs

    Ryan S Phillips, Ian Rosner ... Jonathan E Rubin
    The effects of chloride homeostasis can explain diverse responses of basal ganglia output neurons to putatively inhibitory inputs and may tune these neurons' synchrony, oscillations and behavior in decision-making scenarios.
    1. Neuroscience

    Surface color and predictability determine contextual modulation of V1 firing and gamma oscillations

    Alina Peter, Cem Uran ... Martin Vinck
    Colored surfaces induce strong gamma-synchronization yet sparse firing in V1 when receptive field inputs are predicted from the surrounding spatial context.
    1. Neuroscience

    Angular velocity integration in a fly heading circuit

    Daniel Turner-Evans, Stephanie Wegener ... Vivek Jayaraman
    A distinctive recurrent network motif in the Drosophila central brain enables neurons that encode angular velocity to shift population activity in compass neurons, thereby updating their heading representation whenever the fly turns.
    1. Neuroscience
    2. Physics of Living Systems

    Unsupervised Bayesian Ising Approximation for decoding neural activity and other biological dictionaries

    Damián G Hernández, Samuel J Sober, Ilya Nemenman
    The proposed method deciphers which low-level patterns (such as spikes) control high-level features (behavior) in relative small biological datasets, taking into account the statistical dependencies between such patterns.
    1. Neuroscience

    Slowly evolving dopaminergic activity modulates the moment-to-moment probability of reward-related self-timed movements

    Allison E Hamilos, Giulia Spedicato ... John A Assad
    Dynamic dopaminergic signaling modulates the timing of reward-related movements by tuning the moment-to-moment probability of their onset.
    1. Neuroscience

    Multiple dynamic interactions from basal ganglia direct and indirect pathways mediate action selection

    Hao Li, Xin Jin
    Experimental data and computational simulations reveal a new functional model, that is 'Triple-control' for the basal ganglia pathways in action selection.
    1. Neuroscience

    Human hippocampal CA3 damage disrupts both recent and remote episodic memories

    Thomas D Miller, Trevor T-J Chong ... Clive R Rosenthal
    Human hippocampal cornu ammonis 3 damage impairs both recent and remote autobiographical episodic memory, and disrupts functional integration in medial temporal lobe subsystem regions of the default network.

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