3,202 results found
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structure of the bifunctional secretin complex of Thermus thermophilus

    Edoardo D'Imprima et al.
    The pilus extrusion/DNA uptake system of Thermus thermophilus contains a 13-mer of the 757-residue PilQ protein and a tightly bound protein outside the outer membrane with a role in DNA binding.
    1. Cell Biology
    2. Developmental Biology

    Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation

    Leah C Biggs et al.
    The hair follicle dermal condensate is populated via migration, and the cells exhibit early changes in cell shape and cell cycle status; Fgf20 primes these cellular and molecular events.
    1. Cell Biology

    Cellular hallmarks reveal restricted aerobic metabolism at thermal limits

    Aitana Neves et al.
    Cellular hallmarks of thermal limits are evolutionarily conserved in nematodes, and changes in surface to volume ratio reflect restricted aerobic metabolism at these limits.
    1. Ecology

    Adaptive thermal plasticity enhances sperm and egg performance in a model insect

    Ramakrishnan Vasudeva et al.
    Sperm and egg development are temperature sensitive, enabling males and females to significantly improve their reproductive success by matching gamete function to varying thermal environments for fertilisation and offspring development.
    1. Neuroscience

    Possible magneto-mechanical and magneto-thermal mechanisms of ion channel activation in magnetogenetics

    Mladen Barbic
    Several new magneto-mechanical and magneto-thermal mechanisms of ion channel activation in magnetogenetics are proposed that may explain some of the mysteries that challenge current understanding of the magnetogenetics experiments.
    1. Immunology and Inflammation

    Neonatal-derived IL-17 producing dermal γδ T cells are required to prevent spontaneous atopic dermatitis

    Nicholas A Spidale et al.
    Neonatal-origin dermal Tγδ17 cells are required to maintain normal keratinocytes and prevent spontaneous atopic dermatitis.
    1. Neuroscience

    Human VMPFC encodes early signatures of confidence in perceptual decisions

    Sabina Gherman, Marios G. Philiastides
    Simultaneous EEG-fMRI reveals neural representations of decision confidence unfolding prior to explicit perceptual choices, in a region of the ventromedial prefrontal cortex typically linked to reward processing and value-based decisions.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex

    Brian Bae et al.
    The crystal structure of Thermus transcription activation complexes containing the transcriptional activator CarD reveals a new mechanism for the activation of transcription.
    1. Cell Biology

    Distinct inflammatory and wound healing responses to complex caudal fin injuries of larval zebrafish

    Veronika Miskolci et al.
    Thermal injury and infected wounds induce distinct inflammatory and remodeling mechanisms that alter the dynamics of wound repair.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Consensus designs and thermal stability determinants of a human glutamate transporter

    Erica Cirri et al.
    A fast evolutionary approach to engineer membrane protein kinetic stability yields folded excitatory neurotransmitter transporters and provides insights into their denaturing pathway.

Refine your results by:

Type
Research categories