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48 results found
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1

    Nikolai Hentze et al.
    Heat-induced local unfolding allows Hsf1 to form trimers and bind to DNA, which depends on Hsf1 concentration and is promoted, not inhibited, by Hsp90.
    1. Neuroscience

    Feeding state functionally reconfigures a sensory circuit to drive thermosensory behavioral plasticity

    Asuka Takeishi et al.
    Starvation modulates thermotaxis behaviors in C. elegans via functional reconfiguration of a sensory network by gut-brain signaling.
    1. Neuroscience

    Pan-neuronal screening in Caenorhabditis elegans reveals asymmetric dynamics of AWC neurons is critical for thermal avoidance behavior

    Ippei Kotera et al.
    Functional screening of the entire neuronal network of C. elegans in response to specific stimuli can discover new neural behavior.
    1. Cell Biology
    2. Neuroscience

    Glia actively sculpt sensory neurons by controlled phagocytosis to tune animal behavior

    Stephan Raiders et al.
    A peripheral sense-organ glia actively engulfs fragments of a sensory neuron ending to modify neuron shape and associated animal sensory behavior in Caenorhabditis elegans..
    1. Neuroscience

    Thermosensitive alternative splicing senses and mediates temperature adaptation in Drosophila

    Ane Martin Anduaga et al.
    Temperature controls the circadian clock by directly regulating the alternative splicing of timeless..
    1. Cell Biology
    2. Computational and Systems Biology

    Bistability of a coupled Aurora B kinase-phosphatase system in cell division

    Anatoly V Zaytsev et al.
    Self-activating Aurora B kinase, opposed by an inhibitory phosphatase, forms spatial phosphorylation patterns during cell division.
    1. Neuroscience

    The cation channel TRPA1 tunes mosquito thermotaxis to host temperatures

    Román A Corfas, Leslie B Vosshall
    Female mosquitoes are exquisitely sensitive to human body heat, and the TRPA1 gene is required to focus their attraction toward thermal stimuli resembling warm-blooded hosts.
    1. Neuroscience

    The role of PDF neurons in setting the preferred temperature before dawn in Drosophila

    Xin Tang et al.
    In Drosophila, key neurons controlling sleep play an important role in adjusting the temperature set-point before dawn via time-dependent neuronal plasticity within the clock circuits.
    1. Neuroscience

    The Ionotropic Receptors IR21a and IR25a mediate cool sensing in Drosophila

    Lina Ni et al.
    Two members of a widely studied family of chemoreceptors, the "orphan" chemoreceptor IR21a and its putative co-receptor IR25a, act together to mediate cool sensation in fruit fly larvae.
    1. Neuroscience

    Parabrachial opioidergic projections to preoptic hypothalamus mediate behavioral and physiological thermal defenses

    Aaron J Norris et al.
    Warm-activated parabrachial neurons contain overlapping dynorphin and enkephalin expressing subpopulations, project to preoptic hypothalamus, and mediate behavioral and physiological thermal defenses behaviors.

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