52 results found
    1. Genetics and Genomics
    2. Neuroscience

    Single-cell transcriptome profiles of Drosophila fruitless-expressing neurons from both sexes

    Colleen M Palmateer, Catherina Artikis ... Michelle N Arbeitman
    A single-cell RNA-seq study examining gene expression profiles in neurons that underlie Drosophila reproductive behaviors shows males and females build sex-specific behaviors at the molecular-genetic level by overlaying sex-specific information on core gene expression networks.
    1. Neuroscience

    Network instability dynamics drive a transient bursting period in the developing hippocampus in vivo

    Jürgen Graf, Vahid Rahmati ... Knut Kirmse
    Two-photon Ca2+ imaging and computational modeling reveal major developmental trajectories of spontaneous activity in developing CA1 and identify important roles of network bi-stability and synaptic input characteristics for hippocampal burstiness before eye opening.
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fasting

    Thiruma V Arumugam, Asfa Alli-Shaik ... Jayantha Gunaratne
    Intermittent fasting orchestrates molecular shifts, yielding cardiovascular improvements, revealing novel cardioprotective mechanisms, and suggesting innovative pharmacological strategies for cardiovascular disease prevention and treatment.
    1. Neuroscience

    Bmal1 function in skeletal muscle regulates sleep

    J Christopher Ehlen, Allison J Brager ... Ketema N Paul
    Expression of transcription factor BMAL1 in skeletal muscle reduces the recovery response to sleep loss and is both necessary and sufficient to regulate total sleep amount.
    1. Neuroscience

    A quantitative theory of gamma synchronization in macaque V1

    Eric Lowet, Mark J Roberts ... Peter De Weerd
    Gamma-band synchronization behavior in area V1 was predicted by weakly coupled oscillator principles.
    1. Neuroscience

    Shank3 modulates sleep and expression of circadian transcription factors

    Ashley M Ingiosi, Hannah Schoch ... Lucia Peixoto
    Shank3, a high confidence autism gene candidate, may be a key component of the mechanisms underlying sleep problems in autism.
    1. Neuroscience

    Thalamic reticular control of local sleep in mouse sensory cortex

    Laura MJ Fernandez, Gil Vantomme ... Anita Lüthi
    Local cortical sleep features arise subcortically due to heterogeneous burst discharge in neurons of a sleep rhythm pacemaker previously thought to act uniformly.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Phasic oxygen dynamics confounds fast choline-sensitive biosensor signals in the brain of behaving rodents

    Ricardo M Santos, Anton Sirota
    Fast fluctuations of oxygen, linked to behavioral and neural dynamics in vivo, cause phasic transients is amperometry-measured cholinergic signals via the mechanism of non-steady-state enzyme kinetics in the choline-oxidase-based biosensor.
    1. Neuroscience

    Resonating neurons stabilize heterogeneous grid-cell networks

    Divyansh Mittal, Rishikesh Narayanan
    Intrinsic neuronal resonance stabilizes heterogeneous neural networks by suppressing low-frequency perturbations.
    1. Neuroscience

    Movement-related coupling of human subthalamic nucleus spikes to cortical gamma

    Petra Fischer, Witold J Lipski ... R Mark Richardson
    When coupling between STN spikes and cortical gamma oscillations was strong, subsequent movement was initiated earlier, independent of changes in mean firing rates, demonstrating the importance of relative spike timing.

Refine your results by:

Type
Research categories