Colleen M Palmateer, Catherina Artikis ... Michelle N Arbeitman
A single-cell RNA-seq study examining gene expression profiles in neurons that underlie Drosophila reproductive behaviors shows males and females build sex-specific behaviors at the molecular-genetic level by overlaying sex-specific information on core gene expression networks.
Two-photon Ca2+ imaging and computational modeling reveal major developmental trajectories of spontaneous activity in developing CA1 and identify important roles of network bi-stability and synaptic input characteristics for hippocampal burstiness before eye opening.
J Christopher Ehlen, Allison J Brager ... Ketema N Paul
Expression of transcription factor BMAL1 in skeletal muscle reduces the recovery response to sleep loss and is both necessary and sufficient to regulate total sleep amount.
Local cortical sleep features arise subcortically due to heterogeneous burst discharge in neurons of a sleep rhythm pacemaker previously thought to act uniformly.
Fast fluctuations of oxygen, linked to behavioral and neural dynamics in vivo, cause phasic transients is amperometry-measured cholinergic signals via the mechanism of non-steady-state enzyme kinetics in the choline-oxidase-based biosensor.
Petra Fischer, Witold J Lipski ... R Mark Richardson
When coupling between STN spikes and cortical gamma oscillations was strong, subsequent movement was initiated earlier, independent of changes in mean firing rates, demonstrating the importance of relative spike timing.