Browse the search results

Page 2 of 50
    1. Developmental Biology
    2. Neuroscience

    Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells

    So Goto, Akishi Onishi ... Masayo Takahashi
    Neural retina-derived retinoic acids synthesized by Aldh1a1 control choroidal vascular development by regulating RPE-secreted VEGF.
    1. Developmental Biology
    2. Evolutionary Biology

    Bichir external gills arise via heterochronic shift that accelerates hyoid arch development

    Jan Stundl, Anna Pospisilova ... Robert Cerny
    Unique heterochrony in the cranial segments in bichirs triggers the early formation of their external gills, and might be informative about developmental mechanisms facilitating increased breathing capacity.
    1. Immunology and Inflammation
    2. Neuroscience

    CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization

    Xiao Yang, Lian Zhao ... Wai T Wong
    Vascular degeneration of the choroid and RPE disorganization were associated with pharmacological macrophage ablation, indicating that insufficiency of macrophage function may be a mechanism underlying age- and AMD-associated pathology.
    1. Evolutionary Biology

    A Permian fish reveals widespread distribution of neopterygian-like jaw suspension

    Thodoris Argyriou, Sam Giles, Matt Friedman
    μCT-aided study illuminates the cranial endoskeleton and interrelationships of the Permian actinopterygian †Brachydegma, which is now excluded from crown neopterygians despite exhibiting a double jaw joint.
    1. Neuroscience

    Early life stressful experiences escalate aggressive behavior in adulthood via changes in transthyretin expression and function

    Rohit Singh Rawat, Aksheev Bhambri ... Arpita Konar
    Hypothalamic TTR as a novel molecular player of stress-induced long-term impact on behavior.
    1. Immunology and Inflammation
    2. Neuroscience

    Single-cell profiling reveals periventricular CD56bright NK cell accumulation in multiple sclerosis

    Sabela Rodríguez-Lorenzo, Lynn van Olst ... Helga E de Vries
    Together, our multi-tissue single-cell data shows that CD56bright NK cells accumulate in the periventricular brain regions of multiple sclerosis (MS) patients, bringing NK cells back to the spotlight of MS pathology.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    The transcriptional landscape underlying larval development and metamorphosis in the Malabar grouper (Epinephelus malabaricus)

    Roger Huerlimann, Natacha Roux ... Timothy Ravasi
    Transcriptomic analyses of Malabar grouper show pathways known to be involved in metamorphosis are also upregulated at an early stage of larval development, suggesting an additional function during early development.
    1. Developmental Biology
    2. Evolutionary Biology

    Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea

    Victoria A Sleight, J Andrew Gillis
    Development from dual-origin mesenchyme with common competence explains anatomical parallels and shared patterning of the jawed vertebrate gill arch and paired fin skeletons.
    1. Developmental Biology

    LncEGFL7OS regulates human angiogenesis by interacting with MAX at the EGFL7/miR-126 locus

    Qinbo Zhou, Bo Yu ... Shusheng Wang
    lncEGFL7OS is a lncRNA located at the EGFL7/miR-126 locus that is critical for angiogenesis in humans.
    1. Medicine

    Brain atlas for glycoprotein hormone receptors at single-transcript level

    Vitaly Ryu, Anisa Gumerova ... Mone Zaidi
    The most comprehensive neuroanatomical atlas on the expression of three glycoprotein hormone receptors, namely, TSHRs, LHCGRs, and FSHRs, was mapped using RNAscope, a technology that allows the detection of mRNA at single-transcript level.