Tick-derived sequence variation in the fusion glycoprotein of Crimean-Congo hemorrhagic fever virus (CCHFV) drastically impairs infection of mammalian cells, suggesting that certain CCHFV strains undergo purifying selection in mammalian hosts.

William R Bishai, director of the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), argues that the best place to carry out research into a disease is in its midst.

The rat is much more than a simple model, and a better appreciation of the natural history of wild rats would increase its value as a research organism.

The double-gene-knockout pig is a valuable model to help understand the mechanisms of CD163 and pAPN in the infection of multiple viruses and offers excellent breeding materials for disease-resistant pigs.

The auditory thalamus encodes higher-order information that emerges while learning an auditory discrimination task.

Progenitors establish a single-cell length WNT morphogen gradient to transmit signals directionally and differentially to neighbors.

Super-resolved architectural framework of subdistal appendages surprisingly reveals coupling between distal appendages and subdistal appendages.

Neural pathways from mammalian visual cortex to ancestral brain structures control learning speed and performance of a simple detection task.

Long-term imaging of dentate granule cells reveals that the presence of synaptopodin within large spines, rather than their size, conveys long-term stability to large spines.