1,019 results found
    1. Plant Biology

    A virus responds instantly to the presence of the vector on the host and forms transmission morphs

    Alexandre Martinière, Aurélie Bak ... Martin Drucker
    Cauliflower mosaic virus reacts immediately when aphids feed on the host plant, and this boosts its chances of being taken up and transmitted by the insects to a new plant.
    1. Chromosomes and Gene Expression

    DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

    Benjamin JM Taylor, Serena Nik-Zainal ... Michael S Neuberger
    Enzymes that remove amine groups from cytosine bases in DNA are likely involved in generating the clusters of mutations (kataegis) seen in breast cancer.
  1. Scientific Publishing: The eLife approach to peer review

    Randy Schekman, Fiona Watt, Detlef Weigel
    All editorial decisions at eLife are taken by working scientists in a process that emphasizes fairness, speed and transparency.
    1. Neuroscience

    Decoding the neural mechanisms of human tool use

    Jason P Gallivan, D Adam McLean ... Jody C Culham
    Imaging experiments reveal that some brain regions do not distinguish between actions performed using tools and those performed using the hands, while others represent these two types of action separately.
    1. Structural Biology and Molecular Biophysics

    Viral genome structures are optimal for capsid assembly

    Jason D Perlmutter, Cong Qiao, Michael F Hagan
    Computer simulations reveal that viral nucleic acids have an ideal structure for being packaged into outer protein shells called capsids.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    The autoregulation of a eukaryotic DNA transposon

    Corentin Claeys Bouuaert, Karen Lipkow ... Ronald Chalmers
    A DNA transposon, or ‘jumping gene’, controls its amplification within a genome through a competition between the enzyme multimers that are responsible for its mobility.
  2. Point of View: Making science count in government

    Ian Boyd
    Science is an essential component of policy-making in most areas of government, but the scientific community does not always understand its role in this process.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    TRiC’s tricks inhibit huntingtin aggregation

    Sarah H Shahmoradian, Jesus G Galaz-Montoya ... Wah Chiu
    Cryo-electron tomography reveals how a chaperone protein called TRiC reduces the ability of pathogenic mutant huntingtin proteins to form aggregates.

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