By letting users build interactive simulations directly in a web browser, Artistoo unlocks new ways to communicate, teach, and collaborate in computational biology research.
Unlike in early embryonic development, injured spinal cord and muscle in Xenopus laevis larvae recruit non-canonical Hedgehog signaling essential for their regeneration, while repressing Gli transcriptional activity.
The envelope stress factor DolP associates with the outer membrane protein assembly machinery and supports proper folding and functioning of BamA contributing to preserve envelope integrity.
3D reconstruction for an insect provides new internal structures at nanometer resolution, and the reconstructed feeding insect reveals unexpected contraction of stylet protractors and suggested a novel phloem sap-sucking model.
In the context of susceptibility to severe COVID-19, the observations of a study provide the basis for a personalized interferon-based therapy in patients with rare TLR7 variants.
The mechanism underlying Shprintzen–Goldberg syndrome is solved and reveals that missense mutations in the transcriptional repressor SKI abolish ligand-induced SKI degradation, which results in attenuation of TGF-β transcriptional responses.
Imprinted gene expression is set up during a critical window of early embryonic development, by the translation of parental imprints by oocyte-supplied Smchd1 into allele-specific gene silencing.
